Journal List > Korean J Leg Med > v.37(4) > 1004717

Huh, Ha, Park, and Jang: Fatal Inhalation Injury by Sulfuric Acid Fumes: Case Report

Abstract

Sulfuric acid can cause local or systemic effects after exposure by inhalation, ingestion, or topical application. Direct ingestion is the main exposure route for fatal sulfuric acid injury. Fatal accidents involving the inhalation of toxic sulfuric acid vapors are rare. Inhalation of sulfuric acid fumes causes severe irritation or corrosive damage to the upper respiratory tract. Consequently, severe congestion, edema, and inflammation of the mucous membranes of the upper respiratory passages hinder the entry of air into the lungs, possibly leading to fatalities in victims. A 35-year-old man died at his home after complaining of a severe sore throat. One day earlier, he had worked in a sulfuric acid tank in a copper-smelting plant while wearing an ordinary gas mask that offered no protection against sulfurous acid vapors. Upon autopsy, the larynx and epiglottis showed pronounced edema, congestion, and inflammation that histologically mimicked an acute bacterial suppurative inflammation, accompanied by severe pul-2- monary edema. A field analysis of the air inside the sulfuric acid tank revealed SO4 positivity and a 40% sulfuric acid concentration.

REFERENCES

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Fig. 1.
The epiglottis and larynx show pronounced edema and hemorrhagic spots.
kjlm-37-216f1.tif
Fig. 2.
Microscopic view of the epiglottis shows diffuse infiltration of inflammatory cells in the congested submucosa, accompanied by denuded covering epithelium (H & E, × 100).
kjlm-37-216f2.tif
Fig. 3.
Inflammatory cells in the epiglottis consist of mostly neutrophils and a few eosinophils (H & E, × 100).
kjlm-37-216f3.tif
Fig. 4.
Microscopic view of the lung shows severe edema in alveoli (H & E, × 100).
kjlm-37-216f4.tif
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