Journal List > J Korean Radiol Soc > v.56(1) > 1004367

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Chung, Choi, Kim, Chang, Choi, Lim, Lee, and Park: The Usefulness of Stress Perfusion MR using Steady State Free Precession Sequence for Depiction of Significant Coronary Artery Stenosis
Original Article

Journal of the Korean Radiological Society 2007; 56(1): 25-31.

Published online: 31 January 2007

DOI: https://doi.org/10.3348/jkrs.2007.56.1.25

The Usefulness of Stress Perfusion MR using Steady State Free Precession Sequence for Depiction of Significant Coronary Artery Stenosis

Se-Yeong Chung, M.D., Sang Il Choi, M.D.2, Dong Hoon Kim, M.D.3, Hyuk-Jae Chang, M.D.4, Dong Ju Choi, M.D.4, Cheong Lim, M.D.5, Whal Lee, M.D., Jae-Hyung Park, M.D.

Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.

2Department of Radiology, Seoul National University Bundang Hospital, Korea.

3Department of Radiology, Chosun University, Korea.

4Department of Internal medicine, Division of Cardiology, Seoul National University Bundang Hospital, Korea.

5Department of Thoracic Surgery, Seoul National University Bundang Hospital, Korea.

Address reprint requests to: Sang Il Choi, M.D., Department of Radiology, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea. Tel. 82-31-787-7609, Fax. 82-31-787-4011, drsic@radiol.snu.ac.kr

Copyright © 2007 by The Korean Society of Radiology

Abstract

Purpose

To evaluate the technical performance of stress myocardial perfusion magnetic resonance (MR) imaging using saturation-recovery steady-state free precession (SR- SSFP) and to assess the diagnostic accuracy of this examination for depiction of significant coronary artery stenosis.

Materials and Methods

167 patients underwent stress myocardial perfusion MR imaging at rest and adenosine-induced stress by using a 1.5-T cardiac MR imaging unit. The first-pass MR perfusion was performed using SR-SSFP sequence. Coronary angiography was performed in 113 patients. Image analysis was performed to compare the diagnostic accuracy of MR imaging with that of coronary angiography.

Results

During the MR examination, minor side effects of adenosine-induced stress occurred, most commonly chest discomfort (29%), followed by dyspnea (4%), and facial flushing (0.8%). The overall sensitivity of MR imaging for depicting at least one coronary artery with significant stenosis was 91%. The sensitivities of MR imaging for depiction of stenoses were as follows: 80% for single-vessel stenosis, 81% for double-vessel stenosis, and 100% for triple-vessel stenosis.. The specificity of MR imaging for identification of patients with significant coronary artery stenosis was 78%.

Conclusion

Stress myocardial magnetic resonance (MR) perfusion imaging using SR-SSFP sequence is safe and useful for the detection of significant coronary artery disease.

Keywords: Myocardium, Magnetic resonance (MR), Coronary vessels, diseases

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