Primary liposarcomas of the pleura are extremely rare soft tissue sarcomas, for which radiographic findings have been reported in only a few cases. Although liposarcomas occur most commonly in the lower extremities and retroperitoneum, we encountered a case of pleural liposarcoma arising in the right hemithorax, invading the medial basal segment of the right lower lobe. Thus, herein we report a case of primary pleural liposarcoma, along with a review of the literature.