Abstract
Behcet's disease is a chronic inflammatory disease of an unknown etiology, and it is characterized by recurrent oral and genital ulcerations, eye lesions skin lesions, and other involvement such as gastrointestinal ulcerations and lesions of the central nervous system and major vessels. The vascular lesions include deep vein thrombosis, superficial thrombophlebitis, arterial aneurysm and arterial occlusion. Aortic aneurysm or pseudoaneurysm is a rare complication, but it is one of the most common causes of death in Behcet's disease. We report here on a case of a 43 year old female with Behcet's disease that was complicated by an abdominal aortic pseudoaneurysm, and this was all successfully treated with percutaneous endovascular stent graft insertion, steroid pulse therapy and azathioprine.
REFERENCES
1). Chajek T., Fainarum M. Behcet's disease. Medicine. 1975. 54:179–96.
2). Nakae K., Masaki F., Hashimoto T., Inaba G., Mochizuki M., Sakane T. Recent epidemiological features of Behcet's disease in Japan. In: Wechsler B, Godeau P, eds. Behcet's disease. p. 145-51, Amsterdam, Excerpta Medica. 1993.
3). Shimuzu T. Vascular lesions of Behcet's disease. Cadioangiology. 1977. 1:124.
4). Lie JT. Vascular involvement in Behcet's disease; arterial and venous and vessels of all sizes. J Rheumatol. 1992. 19:341–2.
5). Shimuzu T., Tanaka I. Epidemiological studies on Behcet's syndrome. ShaishinIngku. 1971. 26:451.
6). Park JH., Han MC., Bettmann MA. Arterial manifestations of Behcet's disease. AJR Am J Roentgenol. 1984. 143:821–5.
7). Barlett ST., McCarthy WI., Palmer AS., Flinn WR., Bergan JJ., Yao JS. Multiple aneurysm in Behcet's disease. Arch Surg. 1988. 123:1004–8.
8). Freyrie A., Paragona O., Cennachi G., Pasquinelli G., Guiducci G., Faggioli GL. True and false aneurysm in Behcet's disease. J Vasc Surg. 1993. 17:762–7.
9). Alpagur U., Ugurlucan M., Dayioglu E. Major arterial involvement and review. Ann Vasc Surg. 2007. 21:232–9.
10). Iscan ZH., Vural KM., Bazit M. Compelling nature of arterial manifestations in Behcet disease. J Vasc Surg. 2005. 41:53–8.
11). Kalko Y., Basaran M., Aydin U., Kafa U., Basaranoglu G., Yasar T. The surgical treatment of arterial aneurysms in Behcet's disease: a report of 16 patients. J Vasc Surg. 2005. 42:673–7.
12). Nitecki SS., Ofer A., Karram T., Schwartz H., Engel A., Hoffman A. Abdominal aortic aneurysm in Behcet's disease: new treatment options for an old and challenging problem. Isr Med Assoc J. 2004. ;6;152-5.
13). Park JH., CHung JW., Joh JH., Song SY., Shin SJ., Chung KS, et al. Aortic and arterial aneurysm in Behcet disease: management with stent-graft-initial study. Radiology. 2001. 220:745–50.
14). Liu CW., Ye W., Liu B., Zeng R., Wu W., Dake MD. Endovascular treatment of aortic pseudoaneurysm in Behcet disease. J Vasc Surg. 2009. 50:1029–30.