Journal List > J Korean Rheum Assoc > v.17(4) > 1003762

J Korean Rheum Assoc. 2010 Dec;17(4):412-416. Korean.
Published online December 31, 2010.
Copyright © 2010 The Korean Rheumatism Association
A Case of CPPD Crystal Deposition Disease in a Patient with Rheumatoid Arthritis and Systemic Sclerosis
Jae Shik Jeong, Tae Wook Kim, Min Jeong Jeong, Jun Young Im, Mi Ran Park and Choong Won Lee
Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.

Corresponding author (Email: )
Received May 20, 2010; Revised July 15, 2010; Accepted July 19, 2010.


Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is an inflammatory arthropathy that is defined by the deposition of CPPD crystals in articular and periarticular structures. CPPD crystal deposition disease has various clinical manifestation patterns ranging from an absence of symptoms to a severely destructive arthropathy. CPPD crystal deposition disease very rare with rheumatoid arthritis or systemic sclerosis. We report a case of CPPD crystal deposition disease combined in a patient with rheumatoid arthritis and systemic sclerosis.

Keywords: Rheumatoid arthritis; Calcium pyrophosphate dihydrate crystal deposition disease


Fig. 1
Plain radiographs show punctate and linear radiodense deposits in the fibrocartilaginous periarticular joint articular hyaline cartilage (chondrocalcinosis).
Click for larger image

Fig. 2
Computed tomography scan showing nodular calcified deposit in the distal humerus and proximal ulnar and radius (arrow).
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Fig. 3
Examination of synovial fluid under polarized microscopy shows rhomboid crystals with weakly positive birefringence (wet smear, compensator axis: ↗, A, ×400, B, ×1,000).
Click for larger image

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