A Case of Multiple Gastric Carcinoid in a Woman with Systemic Lupus Erythematosus

Young-Jin Song; Min Young Her; Tae Hee Kim; Ji Hyun Kim; Dong-Yook Kim; Sang-Hyuk Lee; Hye-Kyoung Yoon

doi:10.4078/jkra.2009.16.1.33

Journal List > J Korean Rheum Assoc > v.16(1) > 1003695

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Song, Her, Kim, Kim, Kim, Lee, and Yoon: A Case of Multiple Gastric Carcinoid in a Woman with Systemic Lupus Erythematosus

Original Article

J Korean Rheum Assoc 2009;16(1):33-37.

Published online: 20 March 2009

DOI: https://doi.org/10.4078/jkra.2009.16.1.33

A Case of Multiple Gastric Carcinoid in a Woman with Systemic Lupus Erythematosus

Young-Jin Song¹, Min Young Her¹, Tae Hee Kim¹, Ji Hyun Kim¹, Dong-Yook Kim¹, Sang-Hyuk Lee¹, Hye-Kyoung Yoon²

¹Department of Internal Medicine, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea

²Department of Pathology, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea

Received 18 September 2009 Accepted 4 December 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Gastric carcinoid tumor is a rare neoplasm and it accounts for only 0.3% of all the gastric neoplasms. Gastric carcinoid tumor has high incidence in patients who are aged between 50 and 70 years, and it usually develops over a long period of time. Type I gastric carcinoid tumors are associated with autoimmune atrophic gastritis and pernicious anemia, and there are a few cases of gastric carcinoids in patients with other autoimmune diseases like Sjögren's syndrome and autoimmune thyroiditis. Here, we report on a case of recurrent type I gastric carcinoid tumors in a 42-years old woman who suffered with systemic lupus erythematosus.

Keywords: Systemic lupus erythematosus, Gastric carcinoid tumor, Autoimmune disorder

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Fig. 1.

Endoscopic finding of the stomach. Approximately 0.6∼0.8 cm sized multiple reddish fixed elevated tumors were noted at the great curvature side and the anterior wall of the middle and proximal body of the stomach.

Fig. 2.

Microscopic findings of the gastric biopsy. In the lamina propria, there were irregular cord-like infiltrations of tumor cells (A) and positive reaction for synaptophysin (B) (A: Hematoxylin and eosin stain, ×100, B: Immunohistochemical stain for synpatophysin, ×100).

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