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Abstract
Wegener's granulomatosis is a rare disease that pathologically causes necrotizing granulomatous vasculitis in the arterioles and venules and it can invade the whole body. In addition, it is difficult to distinguish between a nontuberculous mycobacteria infection that shows manifestations of granuloma and Wegener's granulomatosis. There has been no reported on a patient who had the 2 abovementioned two diseases at the same time. A 69 year old male patient had Wegener's granulomatosis that had invaded the prostate. He also had a scrotal swelling and back pain. He had manifestations of granulomatous infection on the scrotum and spine biopsies. However, there was no clinical evidence of Wegener's granulomatosis. As a result, we examined him for other diseases that can cause a granuloma. Consequently, he was also diagnosed as suffering with a nontuberculous mycobacteria infection. We report here on this case and we review the relevant medical literature.
References
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Fig. 1.
(A) The prostate shows a geographically necrotizing granulomatous inflammation. (B) A vasculitis is noted in the small to medium sized vessel. There are many inflammatory cells in the vessel wall and perivascular area (arrow). Fibrinoid necrotic material is noted in the vascular lumen (H&E stain, A ×100, B ×200).
Fig. 3.
(A) An acid fast bacillus (arrow) is noted on the Ziehl-Neelsen stain (A ×1,000), (B) Polymerase chain reaction analysis for NTM. The sample is equal to the result of the positive control (M: mark, P: positive control, S: sample).
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