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Abstract
Neurologic manifestations rarely occur as presenting feature of systemic lupus erythematosus (SLE). We describe two women who presented with several episodes of neurologic symptoms mimicking multiple sclerosis. Several years after disease onset, clinical and laboratory finding were compatible with SLE. These cases show that demyelinating syndrome resembling multiple sclerosis may present as a first manifestation of SLE.
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Fig. 1.
Axial FLAIR weighted brain MRI shows multiple high signal intensity lesions at the periaqueductal gray matter (arrowhead), uncus (thin arrow), third ventricle wall (thick arrow).
Fig. 2.
Sagittal T2-weighted spinal MRI shows high signal intensity lesion in spinal cord at the level of C2-4.
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