Jae Rak Chung; Jae Rak Chung; Eun Ha Kang; Churl Hyun Im; Eun Young Lee; Yun Jong Lee; Yeong Wook Song

doi:10.4078/jkra.2007.14.2.171

Journal List > J Korean Rheum Assoc > v.14(2) > 1003557

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Chung, Chung, Kang, Im, Lee, Lee, and Song: A Case of Henoch-Schönlein Purpura in a Patient with Rheumatoid Arthritis and Chronic Lymphocytic Thyroiditis

Original Article

J Korean Rheum Assoc 2007;14(2):171-175.

Published online: 23 June 2007

DOI: https://doi.org/10.4078/jkra.2007.14.2.171

A Case of Henoch-Schönlein Purpura in a Patient with Rheumatoid Arthritis and Chronic Lymphocytic Thyroiditis

Jae Rak Chung, M.D., Jae Rak Chung, M.D., Eun Ha Kang, M.D., Churl Hyun Im, M.D., Eun Young Lee, M.D., Yun Jong Lee, M.D., Yeong Wook Song, M.D.

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Received 4 January 200727 March 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis involving skin, gut, and kidney associated with arthralgia, arthritis and characterized by immunoglobulin A (IgA)-dominant immune deposits in target organs. This vasculitis is common in children and rarely reported to be associated with other autoimmune disease such as rheumatoid arthritis, autoimmune thyroiditis. We report the case of 72 year-old man who developed adult-onset HSP and also had rheumatoid arthritis and chronic lymphocytic thyroiditis. This is the first report in South Korea.

Keywords: Henoch-Schönlein purpura, Rheumatoid arthritis, Thyroiditis

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Fig. 1.

Purpura in both lower legs.

Fig. 2.

Hand X-ray shows periarticular osteopenia in both hands and marginal erosion adjacent to the right 4th proximal interphalangeal joint.

Fig. 3.

Kidney biopsy demonstrating diffuse proliferative glomerulonephritis with crescent formation (H&E, x 200).

Fig. 4.

The fluorescence microscopic examination shows mesangial and peripheral staining of IgA (IF, x200).

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