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Kim, Jung, Kim, Choi, Park, Chang, and Kim: A Case of Follicular Thyroid Carcinoma Associated with Hemiagenesis of Thyroid Gland
Case Report
Journal of Korean Endocrine Society

Journal of Korean Endocrine Society 2010; 25(1): 46-49.

Published online: 31 March 2010

DOI: https://doi.org/10.3803/jkes.2010.25.1.46

A Case of Follicular Thyroid Carcinoma Associated with Hemiagenesis of Thyroid Gland

Bu-Kyung Kim, Hyun-Joo Jung, Ye-Na Kim, Young-Sik Choi, Yo-Han Park, Hee-Kyoung Chang1, Jeong Hoon Kim2

Department of Internal Medicine, Kosin University College of Medicine, Korea.

1Department of Pathology, Kosin University College of Medicine, Korea.

2Department of Surgery, Kosin University College of Medicine, Korea.

Received 22 June 2009       Accepted 18 July 2009

Copyright © 2010 Korean Endocrine Society

Abstract

Thyroid hemiagenesis is a rare congenital anomaly, in which one thyroid lobe fails to develop. Thyroid hemiagenesis is associated with thyroid diseases such as Graves' disease, Hashimoto's thyroiditis, colloidal goiter and thyroid follicular and papillary cancer. A 53-year-old female patient was diagnosed with a thyroid nodule on health examination. A 99mTc pertechnetate thyroid scan showed absent uptake in the left lobe and cold nodule on the right lobe of thyroid gland. By ultrasonography, we found hemiagenesis in the left thyroid gland and an irregular shaped thyroid nodule on the right lobe of thyroid gland. We performed ultrasonography guided fine needle aspiration and cytologic analysis showed indeterminate nature. Thyroidectomy was performed and finally diagnosed follicular carcinoma of thyroid gland. The authors report this case with a literature review.

Keywords: Follicular cancer, Thyroid hemiagenesis

Figures and Tables

Fig. 1
Ultrasound examination of the thyroid gland in transverse section: Visualization of the right lobe with a hypoechogenic nodule with calcified and irregular margin whereas thyroid tissue on the left side is not observed.
jkes-25-46-g001
Fig. 2
Absence of 99mTc in pertechnate uptake in left lobe that is compatible with thyroid hemiagenesis. A hypoechoic nodule is also seen in the right lobe of thyroid.
jkes-25-46-g002
Fig. 3
A. The microscopic finding shows tumor; follicular neoplasm invasion of severely calcified capsule (H&E stain, ×40), B. The microscopic finding shows tumor of angioinvasion (H&E stain, ×100).
jkes-25-46-g003

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