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Shin, Oh, Jang, Lee, Kim, Min, Lee, Lee, Kim, and Chung: A Case of Hyalinizing Trabecular Adenoma of the Thyroid Gland
Case Report
Journal of Korean Endocrine Society

Journal of Korean Endocrine Society 2009; 24(1): 54-57.

Published online: 31 March 2009

DOI: https://doi.org/10.3803/jkes.2009.24.1.54

A Case of Hyalinizing Trabecular Adenoma of the Thyroid Gland

Hyun Won Shin, Young Lyun Oh1, Hye Won Jang, Ji In Lee, Sun Wook Kim, Yong-Ki Min, Myung-Shik Lee, Moon-Kyu Lee, Kwang-Won Kim, Jae Hoon Chung

Division of Endocrinology & Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.

1Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.

Received 22 October 2008       Accepted 12 November 2008

Copyright © 2009 Korean Endocrine Society

Abstract

Hyalinizing trabecular tumor is a rare benign thyroid tumor first described by Carney et al. in 1987. The tumor is characterized by an encapsulated nodule, trabecular arrangement of polygonal, oval, elongated cells, and hyalinized stroma. It is easily confused with papillary thyroid carcinoma or medullary thyroid carcinoma on surgical and cytologic specimens. A 45-year-old man presented with an incidentally detected left thyroid mass. Fine needle aspiration was performed and papillary thyroid carcinoma was suspected. However, the surgical specimen revealed a hyalinizing trabecular adenoma. We present this hyalinizing trabecular adenoma case to share our experience with physicians and specialists.

Keywords: hyalinizing trabecular tumor, thyroid gland, thyroid neoplasm

Figures and Tables

Fig. 1
Thyroid ultrasonography. Ultrasonographic evaluation shows 0.8 × 0.5 cm indeterminate nodule (A) and small cyst adjacent to the nodule (B) in posterior aspect of left thyroid gland.
jkes-24-54-g001
Fig. 2
Fine needle aspiration and cytology finding. Variable-sized nucleus with intranuclear pseudo-inclusions (indicated with arrow) are noted (H&E stain, ×400).
jkes-24-54-g002
Fig. 3
Histologic finding. Tumor cells are arranged in trabecular pattern separated by stroma (H&E stain, ×200).
jkes-24-54-g003

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