Abstract
Purpose
To compare and confirm the impact of prepregnancy body mass index on pregnancy outcome in women with a singleton conceived by assisted reproductive technology and spontaneously conceived pregnancy.
Methods
A sample of 165 and 247 pregnant women with and without assisted reproductive technology were retrospectively recruited from electronic medical charts of C hospital.
Results
There were significant differences between the two groups for maternal age, paternal age, length of marriage, prepregnancy body mass index, parity, spontaneous abortion experience, and preterm delivery. A prepregnancy body mass index of ≥25 was associated with higher risk for maternal and neonatal complication in the assisted reproductive technology group.
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Table 1.
Characteristics and Pregnancy Outcomes of Pregnant Women with and without ART (N =412)
Table 2.
Characteristics and Pregnancy Outcomes of Pregnant Women with and without ART according to PBMI
Variables | Characteristics | Categories |
PBMI in ART group |
χ2 | p |
PBMI in natural group |
χ2 | p | ||
---|---|---|---|---|---|---|---|---|---|---|
< 25 (n=132) |
≥25 (n=33) |
< 25 (n=223) |
≥25 (n=24) |
|||||||
n (%) | n (%) | n (%) | n (%) | |||||||
General and obstetric characteristics | Age (yr) | < 35 | 53 (40.2) | 14 (42.4) | 0.06 | .845 | 132 (59.2) | 9 (37.5) | 4.16 | .035 |
≥35 | 79 (59.8) | 19 (57.6) | 91 (40.8) | 15 (62.5) | ||||||
Employment | Yes | 77 (58.3) | 22 (66.7) | 0.76 | .431 | 122 (55.0) | 14 (58.3) | 0.10 | .831 | |
No | 55 (41.7) | 11 (33.3) | 100 (45.0) | 10 (41.7) | ||||||
GWG (kg) | Normal | 81 (61.4) | 14 (42.4) | 3.88 | .039 | 115 (51.6) | 14 (58.3) | 0.40 | .668 | |
Abnormal | 51 (38.6) | 19 (57.6) | 108 (48.4) | 10 (41.7) | ||||||
Parity | Primipara* | 69 (52.3) | 16 (48.5) | 0.15 | .703 | 65 (29.1) | 1 (1.5) | 6.91 | .007 | |
Multipara | 63 (47.7) | 17 (51.5) | 158 (70.9) | 23 (95.8) | ||||||
Spontaneous abortion | Yes | 33 (25.0) | 11 (33.3) | 0.94 | .380 | 108 (48.4) | 16 (66.7) | 2.88 | .131 | |
experience | No | 99 (75.0) | 22 (66.7) | 115 (51.6) | 8 (33.3) | |||||
Artificial abortion | Yes | 25 (18.9) | 9 (27.3) | 1.12 | .336 | 41 (18.4) | 8 (33.3) | 3.04 | .104 | |
experience | No | 107 (81.1) | 24 (72.7) | 182 (81.6) | 16 (66.7) | |||||
Maternal outcomes | Maternal complication | Yes* | 14 (10.6) | 10 (30.3) | 8.24 | .010 | 25 (11.2) | 3 (12.5) | 0.04 | .742 |
No | 118 (89.4) | 23 (69.7) | 198 (88.8) | 21 (87.5) | ||||||
Preterm delivery | Yes* | 20 (15.2) | 4 (12.1) | 0.20 | .788 | 10 (4.5) | 3 (12.5) | 2.79 | .120 | |
No | 112 (84.8) | 29 (87.9) | 213 (95.5) | 21 (87.5) | ||||||
Delivery method | NSVD | 64 (48.5) | 14 (42.4) | 0.39 | .564 | 127 (57.0) | 13 (54.2) | 0.07 | .832 | |
C/S | 68 (51.5) | 19 (57.6) | 96 (43.0) | 11 (45.8) | ||||||
Neonatal outcomes | Neonatal complication | Yes* | 5 (3.8) | 4 (12.1) | 3.56 | .080 | 4 (1.8) | 1 (4.2) | 0.62 | .403 |
No | 127 (96.2) | 29 (87.9) | 219 (98.2) | 23 (95.8) | ||||||
Neonatal birth weight | Abnormal* | 16 (12.1) | 3 (9.1) | 0.24 | .768 | 19 (8.5) | 4 (16.7) | 1.70 | .255 | |
Normal | 116 (87.9) | 30 (90.9) | 204 (91.5) | 20 (83.3) |
Table 3.
Odds Ratio for Associations between PBMI and Pregnancy Outcomes