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Lim, Kim, Jeong, Son, Chung, Koh, Lee, Won, Park, Park, Ahn, Kim, Park, Ko, Ahn, and Lee: A Nationwide Survey about the Current Status of Glycemic Control and Complications in Diabetic Patients in 2006 - The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus -
Original Article
Korean Diabetes Journal

Korean Diabetes Journal 2009; 33(1): 48-57.

Published online: 28 February 2009

DOI: https://doi.org/10.4093/kdj.2009.33.1.48

A Nationwide Survey about the Current Status of Glycemic Control and Complications in Diabetic Patients in 2006 - The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus -

Soo Lim1, Dae Jung Kim2, In-Kyung Jeong3, Hyun Shik Son4, Choon Hee Chung5, Gwanpyo Koh6, Dae Ho Lee6, Kyu Chang Won7, Jeong Hyun Park8, Tae Sun Park9, Jihyun Ahn10, Jaetaek Kim10, Keun-Gyu Park11, Seung Hyun Ko12, Yu-Bae Ahn12, Inkyu Lee13

1Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, Korea.

2Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.

3Department of Internal Medicine, Kyung Hee University, East-West Neo Medical Center, Seoul, Korea.

4Department of Internal Medicine, Uijeognbu St. Mary's Hospital, Catholic University Medical College, Uijeongbu, Korea.

5Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.

6Department of Internal Medicine, Cheju National University Hospital, Cheju National University School of Medicine, Jeju, Korea.

7Department of Internal Medicine, Yeungnam University College of Medicine, Yeungnam University Hospital, Daegu, Korea.

8Department of Internal Medicine, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea.

9Department of Internal Medicine, Chonbuk National University Hospital, Jeonju, Korea.

10Department of Internal Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, Korea.

11Department of Internal Medicine, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.

12Department of Internal Medicine, St. Vincent's Hospital, Catholic University Medical College, Suwon, Korea.

13Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

leei@knu.ac.kr

Received 7 July 2008       Accepted 28 January 2009

Copyright © 2009 Korean Diabetes Association

Abstract

Background

The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus performed a nationwide survey about the current status of glycemic control and diabetic complications in 2006.

Methods

The current study included 5,652 diabetic patients recruited from the rosters of endocrinology clinics of 13 tertiary hospitals in Korea. Age, gender, height, weight, waist circumference and blood pressure were investigated by standard method. Fasting and postprandial 2 hour glucose, glycosylated hemoglobin (HbA1c), lipid profiles, fasting insulin and c-peptide levels were measured. Microvascular (microalbuminuria, retinopathy and neuropathy) and macrovascular (coronary artery disease [CAD], cerebrovascular disease [CVD] and peripheral artery disease [PAD]) complications were reviewed in their medical records.

Results

Mean age of total subjects was 58.7 (± 11.6) years and duration of diabetes was 8.8 (0~50) years. Mean fasting and postprandial 2 hour glucose levels were 145.9 ± 55.0 and 208.0 ± 84.4 mg/dL, respectively. Their mean HbA1c was 7.9 ± 1.9%: the percentage of patients within target goal of glycemic control (< 7% of HbA1c) was 36.7%. In this study, 30.3%, 38.3% and 44.6% of patients was found to have microalbuminuria, retinopathy and nephropathy, respectively. Prevalence of CAD, CVD and PAD was 8.7%, 6.7% and 3.0%, respectively. Diabetic complications were closely related with age, duration of diabetes and glycemic control, and this relationship was stronger in microvascular complications than macrovascular ones.

Conclusion

Only about one third of patients with diabetes was found to reach target glycemic control in tertiary hospitals of Korea. More tight control is needed to reduce deleterious complications of diabetes in Korea.

Keywords: Diabetes complications, Diabetes mellitus, Human hemoglobin A1c protein

Figures and Tables

Fig. 1
Glycemic control status evaluated by glycosylated hemoglobin (HbA1c) levels in total subjects.
kdj-33-48-g001
Fig. 2
Prevalence of microvascular and macrovascular complications according to the duration of diabetes.
kdj-33-48-g002
Fig. 3
Prevalence of microvascular and macrovascular complications of diabetes according to the HbA1c level.
kdj-33-48-g003
Fig. 4
Prevalence of macrovascular complication by age groups and by durations of diabetes.
kdj-33-48-g004
Table 1
Clinical and biochemical characteristics in total subject
kdj-33-48-i001

*Mean difference between men and women. †45.1% and 36.7% of subjects had insulin and c-peptide data, respectively. BMI, body mass index; HDL, high density lipoprotein; LDL, low density lipoprotein; NS, not significant; SBP and DBP, systolic and diastolic blood pressure.

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