Journal List > Tuberc Respir Dis > v.71(1) > 1001698

Lee, Kang, Min, Park, Kim, Chung, and Park: A Case of Pulmonary Alveolar Microlithiasis

Abstract

Pulmonary alveolar microlithiasis is a rare disease of unknown etiology that is characterized by the presence of calcific concentrations in the alveolar spaces. The radiographic appearance is pathognomonic. Plain chest radiographs show a white lung or sandstorm lung consisting of fine sand like microcalcifications diffusely scattered throughout both lungs with a higher density at the lung bases. We now report the case of a 67-year-old male whose diagnosis was based on characteristic findings on a chest X-ray and a high-resolution computed tomography scan.

Figures and Tables

Figure 1
Chest radiographs showed widespread small nodules, diffusely involving both the lungs, and commonly described as "sand storm-like". At admission (C), nodules were much increased compare to previous X-rays (A, B).
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Figure 2
High-resolution computed tomography revealed bilateral pleural effusions and diffusely distributed calcified micronodules.
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References

1. Harbitz F. Extensive calcifications of the lungs as distinct disease. Arch Intern Med. 1918. 21:139–146.
2. Thapa R, Ganguly D, Ghosh A. Pulmonary alveolar microlithiasis in siblings. Indian Pediatr. 2008. 45:154–156.
3. Castellana G, Lamorgese V. Pulmonary alveolar microlithiasis. World cases and review of the literature. Respiration. 2003. 70:549–555.
4. Olauson H, Brandenburg V, Larsson TE. Mutation analysis and serum FGF23 level in a patient with pulmonary alveolar microlithiasis. Endocrine. 2010. 37:244–248.
5. Mariotta S, Guidi L, Papale M, Ricci A, Bisetti A. Pulmonary alveolar microlithiasis: review of Italian reports. Eur J Epidemiol. 1997. 13:587–590.
6. Sumikawa H, Johkoh T, Tomiyama N, Hamada S, Koyama M, Tsubamoto M, et al. Pulmonary alveolar microlithiasis: CT and pathologic findings in 10 patients. Monaldi Arch Chest Dis. 2005. 63:59–64.
7. Horvatić Herceg G, Bracić I, Korsić M, Herceg D, Petrović R, Kusacić Kuna S, et al. "Sandstorm" image: bone scintigraphy in pulmonary alveolar microlithiasis. Eur J Nucl Med Mol Imaging. 2009. 36:1353.
8. Pant K, Shah A, Mathur RK, Chhabra SK, Jain SK. Pulmonary alveolar microlithiasis with pleural calcification and nephrolithiasis. Chest. 1990. 98:245–246.
9. Palombini BC, da Silva Porto N, Wallau CU, Camargo JJ. Bronchopulmonary lavage in alveolar microlithiasis. Chest. 1981. 80:242–243.
10. Stamatis G, Zerkowski HR, Doetsch N, Greschuchna D, Konietzko N, Reidemeister JC. Sequential bilateral lung transplantation for pulmonary alveolar microlithiasis. Ann Thorac Surg. 1993. 56:972–975.
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