Journal List > Tuberc Respir Dis > v.70(6) > 1001635

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Kim, Kim, Lee, Lee, Hur, Lee, Lee, Kim, Shin, Shim, In, Kang, and Yoo: A Case of Atypical Bronchial Carcinoid Treated by Cryotherapy
Case Report
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2011; 70(6): 521-525.

Published online: 30 June 2011

DOI: https://doi.org/10.4046/trd.2011.70.6.521

A Case of Atypical Bronchial Carcinoid Treated by Cryotherapy

Hye Ok Kim, M.D., Ph.D., Se Joong Kim, M.D., Ph.D., Seung Hyeun Lee, M.D., Eun Joo Lee, M.D., Ph.D., Gyu Young Hur, M.D., Ph.D., Sung Yong Lee, M.D., Ph.D., Sang Yeub Lee, M.D., Ph.D., Je Hyeong Kim, M.D., Ph.D., Chol Shin, M.D., Ph.D., Jae Jeong Shim, M.D., Ph.D., Kwang Ho In, M.D., Ph.D., Kyung Ho Kang, M.D., Ph.D., Se Hwa Yoo, M.D., Ph.D.

Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

Address for correspondence: Sung Yong Lee, M.D., Ph.D. Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Guro 2-dong, Guro-gu, Seoul 152-703, Korea. Phone: 82-2-2626-3030, Fax: 82-2-2626-1166, syl0801@korea.ac.kr

Received 20 April 2011       Accepted 20 May 2011

Copyright © 2011. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Abstract

Bronchial carcinoid tumors are relatively uncommon neoplasms that are considered to be malignant tumors of low to intermediate grade. They are classified by pathologic features as typical or atypical carcinoids and have distinctly different prognoses and therapeutic options. Surgery is the treatment of choice in typical and atypical carcinoid tumors but the approach has been changing. Recently, several studies have described experiences using other technologies as adjuncts to bronchoscopic resection, technologies such as laser and cryotherapy with curative intent in endoluminal typical carcinoids. Here we present a case of atypical bronchial carcinoid that was treated with bronchoscopic cryotherapy.

Keywords: Carcinoid Tumor, Bronchoscopy, Cryotherapy

Figures and Tables

Figure 1
Chest CT demonstrated focal nodular bronchial wall thickening in distal bronchus intermedius (arrow), just superior aspect of bifurcation of right middle lobe and lower lobe bronchus (A) and a huge mass in liver (B). There was some improvement in nodular lesion in superior segment of right lower bronchus after 9 months (C) and 12 months (D).
trd-70-521-g001
Figure 2
Bronchoscopic findings. (A) and (B) show the opening of superior segment of right lower bronchus was obstructed by fungating intraluminal mass. (C) and (D) show previous cryotherapy site was near completely healed and there was no evidence of recur after 1 year. (A), (C) are white light images and (B), (D) are autofluorescence images.
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Figure 3
(A) The biopsied specimen from the bronchus showed nests of monotonous, round to oval cells with minimal nuclear atypism and prominent nucleoli. Some mitotic figures are found (H&E stain, ×400). (B) These showed positive for CD56 immunohistochemical stain (×400).
trd-70-521-g003

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