Journal List > Tuberc Respir Dis > v.70(4) > 1001604

Kim: Influenza Associated Pneumonia

Abstract

After an outbreak of H1N1 influenza A virus infection in Mexico in late March 2009, the World Health Organization raised its pandemic alert level to phase 6, and to the highest level in June 2009. The pandemic H1N1/A influenza was caused by an H1N1 influenza A virus that represents a quadruple reassortment of two swine strains, one human strain, and one avian strain of influenza. After the first case report of H1N1/A infection in early May 2009, South Korea was overwhelmed by this new kind of influenza H1N1/A pandemic, which resulted in a total of 700,000 formally reported cases and 252 deaths. In this article, clinical characteristics of victims of H1N1/A influenza infection, especially those who developed pneumonia and those who were cared for in the intensive care unit, are described. In addition, guidelines for the treatment of H1N1/A influenza virus infection victims in the ICU, which was suggested by the Korean Society of Critical Care Medicine, are introduced.

Figures and Tables

Figure 1
History of reassortment events in the evolution of the 2009 influenza A (H1N1) virus.
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Table 1
Multivariate analysis for survival predictors of patients with H1N1-associated pneumonia
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CI: confidence interval; BUN: blood urea nitrogen.

Table 2
Baseline characteristics of critically ill patients with pandemic influenza A/H1N1
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Values are presented as number (%) or mean±SD unless otherwise indicated.

SD: standard deviation.

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