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Choi, Kim, Park, Park, Choi, Lee, and An: A Case of Lipoid Pneumonia Associated with Silicon Oil Injection into Breast
Case Report
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2010; 69(4): 288-292.

Published online: 31 October 2010

DOI: https://doi.org/10.4046/trd.2010.69.4.288

A Case of Lipoid Pneumonia Associated with Silicon Oil Injection into Breast

Jae Hyeon Choi, M.D.1, Mi Kyoung Kim, M.D.1, Jae Geun Park, M.D.1, Yong Kun Park, M.D.2, Kang Hyeon Choi, M.D.1, 3, Ki Man Lee, M.D.1, 3, Jin Young An, M.D.1, 3

1Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine, Cheongju, Korea.

2Department of Internal Medicine, The Cheongju St. Mary's Hospital, Cheongju, Korea.

3Chungcheong Respiratory Institute, Cheongju, Korea.

Address for correspondence: Jin Young An, M.D. Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine, 410, Gaeshin-dong, Heungdug-gu, Cheongju 361-711, Korea. Phone: 82-43-269-6308, Fax: 82-43-269-6308, drahnjy@chungbuk.ac.kr

Received 3 May 2010       Accepted 1 June 2010

Copyright © 2010. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Abstract

Exogenous lipoid pneumonia occurs rarely in healthy people. In most cases, exogenous lipoid pneumonia is usually caused by aspiration of mineral, vegetable, or animal oil. We report the case of 42-year-old woman, who have experienced lipoid pneumonia after silicon injection into her breast for cosmetic purposes. The patient experienced fever, dyspnea, sputum, and hemoptysis after silicon injection into her breast. Chest computed tomography demonstrated non-segmental distribution of bilateral consolidation in both lung fields. A transbronchial lung biopsy specimen shows foamy microphages in alveolar spaces. Papanicolaous staining of bronchoalveolar lavage fluid showed abundant foamy marcrophages and many neutrophils. With these results, we confirmed lipoid pneumonia was associated with silicon oil injection into breast.

Keywords: Pneumonia, Lipid, Mammoplasty, Silicone Oils

Figures and Tables

Figure 1
Chest radiography in a 42-year-old woman with hemoptysis and dyspnea. (A) The initial chest PA shows ill defined consolidation in both middle and lower lung field. (B) Chest lateral radiography shows main haziness in anterior portion of lung. (C) In admission 8 days later, chest PA shows improving of consolidation in both middle and lower luing field.
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Figure 2
Chest CT shows non-segmental distribution of bilateral consolidation in both lung field.
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Figure 3
Bronchoscopic findings. Bronchoscope shows mucosal edema, flush, bleeding in left upper lobe (LUL) bronchus (A) and right middle lobe (RML) and right lower lobe (RLL) bronchus (B).
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Figure 4
TBLB and BAL fluid slide. (A) TBLB shows foamy macrophage in alveolar spaces (H&E stain, ×40). (B) Papanicolaous staining of bronchoalveolar lavage fluid shows abundant foamy marcrophage and mixed with many neutrophils (cytospin preparation; ×40).
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Figure 5
Chemical analysis by FTIR and Pyrolyzer-Gas chromatography. It means almost same material among three specimen. (A) General sylicon oil. (B) Injection oil to patient. (C) Tissue extract from patient.
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