Journal List > Tuberc Respir Dis > v.69(4) > 1001546

Choi, Kim, Park, Park, Choi, Lee, and An: A Case of Lipoid Pneumonia Associated with Silicon Oil Injection into Breast


Exogenous lipoid pneumonia occurs rarely in healthy people. In most cases, exogenous lipoid pneumonia is usually caused by aspiration of mineral, vegetable, or animal oil. We report the case of 42-year-old woman, who have experienced lipoid pneumonia after silicon injection into her breast for cosmetic purposes. The patient experienced fever, dyspnea, sputum, and hemoptysis after silicon injection into her breast. Chest computed tomography demonstrated non-segmental distribution of bilateral consolidation in both lung fields. A transbronchial lung biopsy specimen shows foamy microphages in alveolar spaces. Papanicolaous staining of bronchoalveolar lavage fluid showed abundant foamy marcrophages and many neutrophils. With these results, we confirmed lipoid pneumonia was associated with silicon oil injection into breast.

Figures and Tables

Figure 1
Chest radiography in a 42-year-old woman with hemoptysis and dyspnea. (A) The initial chest PA shows ill defined consolidation in both middle and lower lung field. (B) Chest lateral radiography shows main haziness in anterior portion of lung. (C) In admission 8 days later, chest PA shows improving of consolidation in both middle and lower luing field.
Figure 2
Chest CT shows non-segmental distribution of bilateral consolidation in both lung field.
Figure 3
Bronchoscopic findings. Bronchoscope shows mucosal edema, flush, bleeding in left upper lobe (LUL) bronchus (A) and right middle lobe (RML) and right lower lobe (RLL) bronchus (B).
Figure 4
TBLB and BAL fluid slide. (A) TBLB shows foamy macrophage in alveolar spaces (H&E stain, ×40). (B) Papanicolaous staining of bronchoalveolar lavage fluid shows abundant foamy marcrophage and mixed with many neutrophils (cytospin preparation; ×40).
Figure 5
Chemical analysis by FTIR and Pyrolyzer-Gas chromatography. It means almost same material among three specimen. (A) General sylicon oil. (B) Injection oil to patient. (C) Tissue extract from patient.


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