Journal List > Tuberc Respir Dis > v.68(4) > 1001492

Kim, Kim, Jeun, Park, Jang, Lee, Ryu, Sim, and Chun: A Case of Node-bronchial Fistula by Non-small Cell Lung Cancer

Abstract

Lymphadenopathy in the thoracic cavity is frequently caused by inflammatory diseases. In very rare cases, the node-bronchial fistula has been reported to be the cause of complications of pulmonary tuberculosis. A male patient with necrotizing pneumonia and mediastinal lymph node enlargements identified by chest computed tomography was also found to have a node-bronchial fistula caused by lung cancer. The patient was treated for tuberculosis with pneumonia for one week before a definitive diagnosis was made. A further investigation revealed him to have non-small cell lung cancer (NSCLC, adenocarcinoma) and multiple mediastinal lymphadenopathies accompanied with the node-bronchial fistula. We report this specific case that had been previously treated for tuberculosis but was later revealed to be NSCLC accompanied with a node-bronchial fistula.

Figures and Tables

Figure 1
Chest X-ray on admission showed multiple consolidations in right upper lung zone and left lingular lobe.
trd-68-231-g001
Figure 2
Chest CT scan revealed subcarinal lymph node enlargement with air bubbles (possible node-bronchial fistula between airway and subcarinal lymph node). Multiple necrotic lymph nodes enlargement were seen in mediastium, both hilar, retrosternal and lower cervical area.
trd-68-231-g002
Figure 3
Chest CT scan during follow up periods revealed that the size of lymph node at subcarinal area was decreased but another lymph nodes showed variable response.
trd-68-231-g003
Figure 4
Chest X-ray on hospital day 32 showed improvement of consolidation in both lung fields.
trd-68-231-g004

References

1. Im JG, Lee KS. The chest radiology. 2000. 1st ed. Seoul: Ilchokak.
2. Iselin H, Suter F. The role of perforation of hilar lymph nodes into the bronchial tree of adults. Chest. 1954. 25:302–311.
3. Jiang B, Wu GP, Zhao YJ, Wang SC. Transcription expression and clinical significance of TTF-1 mRNA in pleural effusion of patients with lung cancer. Diagn Cytopathol. 2008. 36:849–854.
4. Mountain CF, Dresler CM. Regional lymph node classification for lung cancer staging. Chest. 1997. 111:1718–1723.
5. Lois M, Noppen M. Bronchopleural fistulas: an overview of the problem with special focus on endoscopic management. Chest. 2005. 128:3955–3965.
6. Park EH, Jang TW, Park MI, Song JY, Choi IS, Oak CH, et al. A case of esophago-mediatinal fistula due to esophageal tuberculosis. Tuberc Respir Dis. 2007. 62:531–535.
7. Gu P, Zhao YZ, Jiang LY, Zhang W, Xin Y, Han BH. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. Eur J Cancer. 2009. 45:1389–1396.
8. Zwischenberger JB, Savage C, Alpard SK, Anderson CM, Marroquin S, Goodacre BW. Mediastinal transthoracic needle and core lymph node biopsy: should it replace mediastinoscopy? Chest. 2002. 121:1165–1170.
9. Wang MZ, Wan XB, Chen Y, Zhang L, Zhong W, Zhong X, et al. The results of transbronchial needle aspiration in 164 cases with enlarged mediastinal and/or hilar lymph nodes. Zhonghua Nei Ke Za Zhi. 2009. 48:133–135.
10. Fritscher-Ravens A, Bohuslavizki KH, Brandt L, Bobrowski C, Lund C, Knofel WT, et al. Mediastinal lymph node involvement in potentially resectable lung cancer: comparison of CT, positron emission tomography, and endoscopic ultrasonography with and without fine-needle aspiration. Chest. 2003. 123:442–451.
TOOLS
ORCID iDs

Jin Hwa Lee
https://orcid.org/http://orcid.org/0000-0003-0843-9862

Similar articles