Journal List > Tuberc Respir Dis > v.65(5) > 1001306

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Kim, Kang, Kim, Park, Baek, Choi, Shin, Kim, Park, Jeung, Hur, Lee, Lee, Kim, Lee, Lee, Yum, and Choi: A Case of Recurrent Pneumonitis Caused by Bojungikgitang(Bu-Zhong-Yi-Qi-Tang)
Case Report
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2008; 65(5): 416-420.

Published online: 30 November 2008

DOI: https://doi.org/10.4046/trd.2008.65.5.416

A Case of Recurrent Pneumonitis Caused by Bojungikgitang(Bu-Zhong-Yi-Qi-Tang)

Seung Gu Kim, M.D.1, Gun Hi Kang, M.D.1, Jun Jae Kim, M.D.1, Hyun Park, M.D.1, Na Na Baek, M.D.1, Sang Bong Choi, M.D.1, Eun Ah Shin, M.D.2, Joung Sook Kim, M.D.3, I Nae Park, M.D.1, Hoon Jeung, M.D.1, Jin Won Hur, M.D.1, Sung Soon Lee, M.D.1, Hyun Kyung Lee, M.D.1, Joo In Kim, M.D.1, Young Min Lee, M.D.1, Hyuk Pyo Lee, M.D.1, Ho Kee Yum, M.D.1, Soo Jeon Choi, M.D.1

1Department of Internal Medicine, Paik Hospital, Inje University College of Medicine, Seoul, Korea.

2Department of Pathology, Paik Hospital, Inje University College of Medicine, Seoul, Korea.

3Department of Radiology, Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Address for correspondence: Soo Jeon Choi, M.D. Department of Internal Medicine, Inje University Sanggye Paik Hospital, 761-1, Sanggye 7-dong, Nowon-gu, Seoul 139-707, Korea. Phone: 82-2-950-1990, Fax: 82-2-950-1954, choisj@paik.ac.kr

Received 22 August 2008       Accepted 24 September 2008

Copyright © 2008 The Korean Academy of Tuberculosis and Respiratory Diseases

Abstract

Many classes of drug, such as antineoplastic drugs and antiarrhythmic drugs, have potential to induce interstitial lung disease. Herbal medicines are also believed to have the potential to induce pneumonitis. However, to our knowledge, there are no reports of pneumonitis caused by herbal medications in the Korean medical database. We report a case of recurrent pneumonitis caused by a self rechallenge of the Herbal medicine Bojungikgitang (Bu-Zhong-Yi-Qi-Tang : Hochu-ekki-to).

Keywords: Pneumonitis, Herbal medicine, Bu-Zhong-Yi-Qi-Tang (Hochu-ekki-to)

Figures and Tables

Figure 1
Chest PA shows diffuse bilateral haziness in both lower lobes with decreased lung volume.
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Figure 2
Chest HRCT scan on admission. HRCT shows bilateral peribronchial and subpleural ground glass opacities with mild bronchial dilatation in both lungs.
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Figure 3
Pathologic findings of transbronchial lung biopsy shows mild interstitial fibrosis with lymphocytic infiltration (H&E stain, ×200) (A) and focal intra-alveolar histiocytic aggregation (H&E stain, ×200) (B).
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Figure 4
Chest PA findings after methylprednisolone pulse therapy. Findings of previous bilateral haziness, linear atelectasis and cardiomegaly were marked improved compared to admission day, and those findings were went on.
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Figure 5
Chest PA shows relapsed bilateral haziness in both lower lobes, after retreatment of Bojungikitang.
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Figure 6
Chest PA findings after methylprednisolone treatment. Bilateral haziness was cleared.
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