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Min, Yoon, Park, Kim, Rhee, Yoo, Kim, Han, Shim, and Yim: A Case of Chronic Necrotizing Pulmonary Aspergillosis Obscured by Cavitary Pulmonary Tuberculosis
Case Report
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2007; 63(4): 368-371.

Published online: 31 October 2007

DOI: https://doi.org/10.4046/trd.2007.63.4.368

A Case of Chronic Necrotizing Pulmonary Aspergillosis Obscured by Cavitary Pulmonary Tuberculosis

Joo-Won Min, M.D., Young Soon Yoon, M.D., Jong Sun Park, M.D., Hye-Ryoun Kim, M.D., Ji young Rhee, M.D., Chul-Gyu Yoo, M.D., Young Whan Kim, M.D., Sung Koo Han, M.D., Young-Soo Shim, M.D., Jae-Joon Yim, M.D.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul, Korea.

Address for correspondence: Jae-Joon Yim, M.D. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea. Phone: 82-2-2072-2059, Fax: 82-2-762-9662, yimjj@snu.ac.kr

Received 25 July 2007       Accepted 31 August 2007

Copyright © 2007 The Korean Academy of Tuberculosis and Respiratory Diseases

Abstract

Pulmonary cavities are caused by bacterial pneumonia, fungal diseases, lung cancer, and tuberculosis (TB). However, in Korea, patients with cavitary lung lesions are generally considered to have pulmonary TB, where the incidence of TB is approximately 70/100,000 per year. We report a case of chronic necrotizing pulmonary aspergillosis that was obscured by multidrug-resistant pulmonary TB.

Keywords: Tuberculosis, Aspergillosis, Pulmonary cavity

Figures and Tables

Figure 1
Initial CT shows cavitary lesion with air space consolidation, left. Follow-up CT after 2 months of anti-tuberculosis medication revealed aggravated lesion, right.
trd-63-368-g001
Figure 2
Resected lung tissue shows 5 cm sized cavity filled with necrotic materials accompanied with dense peripheral fibrosis.
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Figure 3
Microscopic view of resected lung tissue. Fungal hyphae are seen in the left upper area, H&E stain(×200), left. GMS stain (×400), right.
trd-63-368-g003

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