Journal List > Tuberc Respir Dis > v.62(4) > 1001081

Lim, Sim, Lee, Kim, Ryu, Chun, Kim, Lee, Sung, Ahn, and Chang: Synchronous Double Primary Cancers of Lung and Liver

Abstract

Although reports of multiple primary malignant tumors have increased recently, cases of synchronous double primary tumors of lung and liver are rare. A 73-year-old man suffered from chronic cough. His chest x-ray showed segmental atelectasis of the right upper lobe. Bronchoscopy revealed a mass occluding the orifice of the anterior segmental bronchus of the right upper lobe, and a biopsy showed a squamous cell carcinoma. A synchronous hepatic mass was found by ultrasonography. However, F18-FDG-PET showed no evidence of a distant metastasis. The liver biopsy revealed a hepatocellular carcinoma. A right upper lobe lobectomy and a sleeve resection were performed for the lung cancer, and radiofrequency ablation was performed for the hepatocellular carcinoma.

Figures and Tables

Figure 1
Chest radiograph shows increased radio-opacity in anterior segment of the right upper lobe.
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Figure 2
Computed tomogram of the chest shows occlusion of right upper lobe bronchus with atelectasis without a definite mass. There are calcified lymph nodes around right upper lobe bronchus and mediastinum and hilar area.
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Figure 3
Ultrasonography of liver shows an about 1.91 cm-sized hypoechoic mass with indistinct margin, which includes echogenic portion.
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Figure 4
F18-FDG positron emission tomogram of whole body shows diffuse mild FDG uptake in segmental atelectasis of the right upper lobe, which includes a focal nodular lesion (SUV=4.1) in the proximal portion. There are hypermetabolic lesions in right lower paratracheal and subcarinal area (SUV=2.9, 2.5). Increased FDG uptake is also seen around right hip prosthesis.
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Figure 5
Bronchoscopy shows a mass occluding the orifice of anterior segmental bronchus of right upper lobe.
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Figure 6
(A) Bronchoscopic lung biopsy specimen shows moderately differentiated squamous cell carcinoma of keratinizing type (HE stain, ×400). (B) Liver biopsy specimen shows well differentiated hepatocellular carcinoma (HE stain, ×400).
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