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Lee, Chung, Chang, Kim, Kim, Chang, Kim, and Ahn: Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer
Original Article
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2007; 62(4): 284-289.

Published online: 30 April 2007

DOI: https://doi.org/10.4046/trd.2007.62.4.284

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer

Chang Youl Lee, M.D.1, Jae Hee Chung, M.D.1, Yoon Soo Chang, M.D.1, Se Kyu Kim, M.D.1, 2, Hyung Jung Kim, M.D.1, 2, Joon Chang, M.D.1, 2, Sung Kyu Kim, M.D.1, 2, Chul Min Ahn, M.D.1, 2

1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

2THuman Barrier Research Center, Yonsei University College of Medicine, Seoul, Korea.

Adress for correspondence: Chul Min Ahn, M.D. Yongdong Severance Hospital, Department of Internal Medicine, Yonsei University College of Medicine, Kangnam P.O. Box 1217, Seoul, Korea. Phone: 82-2-2019-3317, Fax: 82-2-3463-3882, ahnswine@naver.com

Received 8 February 2007       Accepted 26 March 2007

Copyright © 2007 The Korean Academy of Tuberculosis and Respiratory Diseases

Abstract

Background

To define the clinical features of patients with lung and upper aerodigestive tract cancer through a review of the histopathology, clinical features and follow-up results.

Methods

Patients with lung and upper aerodigestive tract cancer who were diagnosed in Young dong Severance Hospital from 1992 to 2005, were retrospectively reviewed. The clinical data, radiologic findings, pathologic findings, treatment modalities were evaluated.

Results

There was a total of 20 patients with aerodigestive tract cancer who were diagnosed with lung cancer over a 13 years period. The mean age was 58.45 ± 15.09 years and 19 cases were male. There were 14 smokers with an average pack year of 46 years. Twelve patients had aerodigestive tract cancer and later developed lung cancer, and 5 lung cancer patients were later diagnosed with aerodigestive tract cancer.

Conclusion

These results suggest that cancers of the aerodigestive tract and lung can arise as either dependent or independent events and most aerodigestive tract cancer patients who developed lung cancer are not treated properly. Therefore, regular low dose chest CT with close suspicion is needed to properly manage upper aerodigestive tract cancer patients.

Keywords: Aerodigestive tract cancer, Lung cancer, Clinical feature

Figures and Tables

Table 1
Clinical fearures of UADT and lung cancer, 20 cases
trd-62-284-i001

*First UADT cancer and second lung cancer †First lung cancer and second UADT cancer ‡First UADT cancer and lung cancer

Table 2
Diagnosis sequence and interval time of UADT and lung cancer
trd-62-284-i002

p<0.05

Table 3
Clinical symptoms
trd-62-284-i003
Table 4
Treatment of second lung cancer
trd-62-284-i004

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