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Lee, Lee, Kim, Min, Park, Lee, Rhee, and Lee: A Case of Huge Pulmonary Blastoma With Multiorgan Invasion
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Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2007; 62(2): 149-153.

Published online: 28 February 2007

DOI: https://doi.org/10.4046/trd.2007.62.2.149

A Case of Huge Pulmonary Blastoma With Multiorgan Invasion

Tae Hwan Lee, M.D., Ka Young Lee, M.D., So Ri Kim, M.D., Kyung Hun Min, M.D., Seoung Ju Park, M.D., Heung Bum Lee, M.D., Yang Keun Rhee, M.D., Yong Chul Lee, M.D., Ph.D.

Department of Internal Medicine and Airway Remodeling Laboratory, Chonbuk National University Medical School, Jeonju, Republic of Korea.

Corresponding Author: Yong Chul Lee, M.D., Ph.D., Department of Internal Medicine, Chonbuk National University Medical School, San 2-20 Geumam-dong, Deokjin-gu, Jeonju, Jeonbuk 561-180, Republic of Korea. Phone: 82-63-250-1664; Fax: 82-63-254-1609; leeyc@chonbuk.ac.kr

Received 29 November 2006       Accepted 27 December 2006

Copyright © 2007 The Korean Academy of Tuberculosis and Respiratory Diseases

Abstract

A pulmonary blastoma is a rare malignant tumor of the lung that is composed of epithelial and mesenchymal elements and resembles the structure of an embryonic lung. Pulmonary blastomas have a very poor prognosis and make up 0.25 to 0.5 percent of all primary malignant lung tumors. A pulmonary blastoma usually manifests as a solitary parenchymal mass or nodule and multiple subpleural mass with effusion on chest X-ray and computed tomography. We encountered a very rare case of pulmonary blastoma in a 52 years old male. He complained of abdominal pain, fullness, and dyspnea. The radiology examination revealed a huge lung mass invading the mediastinum, heart, diaphragm, and liver. The percutaneous needle biopsies were performed, and this tumor was diagnosed as a pulmonary blastoma. We report a biopsy confirmed case of a huge pulmonary blastoma invading multiple organs.

Keywords: Pulmonary blastoma, Lung cancer, Metastasis

Figures and Tables

Figure 1
Chest radiographs show a huge mass on right lower lung field. (A) Posteroanterior view, (B) Lateral view of left side
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Figure 2
A CT scan shows a huge mass (14 × 12 × 11 cm) in the right lower lobe invading diaphragm and liver. (A) Enhanced axial view of CT scan (B) Coronal view of CT scan
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Figure 3
PET-CT scan shows unevenly hypermetabolic (p-SUV=8.34) huge mass in the right lower lobe invading mediastinum, diaphragm, and liver.
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Figure 4
Photomicrograph of tissues obtained from percutaneous liver biopsy shows characteristic features of malignant stromal structure composed with undifferenciated small round cells and loose spindle cells. H&E stain (× 100).
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Figure 5
Immunohistochemical stain for vimentin and CD99 of tissues obtained from percutaneous liver biopsy shows positive reaction in tumor cells (× 100).
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Figure 6
Photomicrograph of tissues obtained from percutaneous transthoracic needle biopsy shows a malignant stromal structure composed with undifferenciated and immature celluar component. (A) H&E stain (× 100), (B) H&E stain (× 200).
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