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Lee, Gong, Joo, Lee, Kim, and Ahn: A Case of Recurred Uterine Cervical Cancer Presented as Only Huge Mediastinal Mass
Case Report
Tuberculosis and Respiratory Diseases

Tuberculosis and Respiratory Diseases 2006; 60(6): 684-689.

Published online: 30 June 2006

DOI: https://doi.org/10.4046/trd.2006.60.6.684

A Case of Recurred Uterine Cervical Cancer Presented as Only Huge Mediastinal Mass

Jun Seok Lee, M.D., Soo Jung Gong, M.D., Jong Eun Joo, M.D.1, Jung Ae Lee, M.D., Jeong Seon Kim, M.D., Young Soo Ahn, M.D.

Department of Internal Medicine, Eulji University School of Medicine, Seoul, Korea.

1Department of Pathology, Eulji University School of Medicine, Seoul, Korea.

Address for correspondence: Soo Jung Gong, M.D., Department of Internal Medicine, Eulji University School of Medicine, Eulji Medical Center, 280-1, Hagye-1 dong, Nowon gu, Seoul, Korea. Phone: 82-2-970-8206, Fax: 82-2-970-8621, gsj1117@eulji.or.kr

Received 14 April 2006       Accepted 9 June 2006

Copyright © 2006 The Korean Academy of Tuberculosis and Respiratory Diseases

Abstract

Uterine cervical cancer is the 5th most common malignancy in Korean women. With the development of new diagnostic and therapeutic modalities, earlier stage cancers are being diagnosed with longer survival rates being anticipated. Accordingly, recurrent cancers are being encountered more often in clinical practice. Most recurrent uterine cervical cancer patients, have intra-pelvic lesions and adjacent lymph node involvement, while a distant metastasis alone is extremely rare. A mediastinal recurrence of uterine cervical cancer is not common with most manifesting as small lymph node enlargements. We report a case of a 46-year-old woman with recurrent uterine cervical cancer presenting only as a huge mediastinal mass without a local recurrence.

Keywords: Mediastinal mass, Uterine cervical cancer, Recurrence

Figures and Tables

Figure 1
Chest PA showed linear atelectasis and calcification in left lower lung field.
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Figure 2
Chest CT scan revealed anterior mediastinal mass and left pleural effusion.
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Figure 3
Microscopic study revealed diffuse infiltrating squamous cell nests with central necrosis of squamous cell carcinoma, large cell nonkeratinizing type in the mediastinal mass (H&E stain, A: ×100, B: ×200) and the same type of squamous cell carcinoma of in the uterine cervix 4 years ago (H&E stain, C: ×100, D: ×200).
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Figure 4
Human papilloma virus DNA chip sheet showed positivity for 16 genotype in mediastinal mass.
trd-60-684-g004

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