Journal List > Tuberc Respir Dis > v.59(6) > 1000892

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Lim, Bae, Cho, Kang, Lee, Kim, Kim, Kwak, and Kim: A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma
Case Report

Tuberculosis and Respiratory Diseases 2005; 59(6): 679-683.

Published online: 31 December 2005

DOI: https://doi.org/10.4046/trd.2005.59.6.679

A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma

Seongmin Lim, M.D., Jongoh Bae, M.D., Sanggeon Cho, M.D., Sanggu Kang, M.D., Eunyoung Lee, M.D., Sungkuk Kim, M.D.1, Young Kim, M.D., Jinyoung Kwak, Kwiwan Kim1,

Department of Internal medicine, Presbyterian Medical Center, Jeonju, Korea.

2Department of Internal medicine, Chonbuk National University Medical School, Korea.

3Kim kwiwan Medical Clinic, Jeonju, Korea.

Address for correspondence: Kwak Jinyoung M.D., Department of internal medicine, Presbyterian medical center, Junghwasandong, Wansangu, Jeonju, Jeonlabukdo, Korea. Phone: 063)230-8919, Fax: 063)230-8917, drnbear@gmail.com

Received 4 October 2005       Accepted 24 October 2005

Copyright©2005. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Abstract

Cancer associated retinopathy (CAR) syndrome is a very rare ocular manifestation of paraneoplastic syndrome, and is characterized clinically by progressive visual impairment. Immune cross-reactivity between antigens in the cancerous tissue and antigens in the retina may play an important role in its pathogenesis, and most of cases are associated with lung carcinoma, particularly small cell lung cancer. The clinical triad of CAR is described as photosensitivity, ring scotomata, and an attenuated retinal arterial caliber.
Here, we report a 61-year old male patient with CAR syndrome, who had small cell lung carcinoma in the stage of limited disease, with a brief review of the relevant literature.

Keywords: Cancer associated retinopathy, CAR syndrome, Paraneoplastic syndrome, Small cell lung cancer

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