Journal List > Tuberc Respir Dis > v.57(3) > 1000691

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Hwang, Oh, Kim, Kim, Yoon, and Song: A Case of Central Diabetes Insipidus in Patient with Non-small Cell Lung Cancer
Original Article

Tuberculosis and Respiratory Diseases 2004; 57(3): 284-288.

Published online: 30 September 2004

DOI: https://doi.org/10.4046/trd.2004.57.3.284

A Case of Central Diabetes Insipidus in Patient with Non-small Cell Lung Cancer

Eun Mi Hwang, M.D., You Kyoung Oh, M.D., Ki Jo Kim, M.D., Yong Hyun Kim, M.D., Hyoung Kyu Yoon, M.D., Jeong Sup Song, M.D.

Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea.

Address for correspondence: Jeong Sup Song, M.D. Department of Internal Medicine, St. Mary's Hospital, Catholic University. College of Medicine, 150-713, #62 Yeoido-dong, Youngdeungpo-ku, Seoul, Korea. Phone: 02-3779-1146, Fax: 02-780-3132, jssong@catholic.ac.kr

Received 29 January 2004       Accepted 19 July 2004

Copyright©2004. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Abstract

Central diabetes insipidus (DI) is a disease caused by insufficient release of antidiuretic hormone. Central DI with lung cancer is very rare. Most of them are caused by the pituitary metastasis, and rarely, by the paraneoplastic syndromes. Central DI is diagnosed by the water deprivation test. The treatment consists of surgical resection, radiotherapy and administration of desmopressin.
We report an unusual case of central DI with non-small cell lung cancer. The diagnosis was confirmed by water deprivation test. After the administration of desmopressin, the urine osmolarity was increased. The patient's symptoms and urine osmolarity were improved by intranasal desmopressin.

Keywords: Non-small cell lung cancer, Central diabetes insipidus

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