Journal List > Korean J Obstet Gynecol > v.54(5) > 1088275

TOOLS
Kim, Kwak, Byun, Park, Park, Park, Jun, and Syn: A case of vaginally terminated fetus who had intracranial immature teratoma after transabdominal fetal cephalocentesis
Case Report
Korean Journal of Obstetrics & Gynecology

Korean Journal of Obstetrics & Gynecology 2011; 54(5): 247-251.

Published online: 25 May 2011

DOI: https://doi.org/10.5468/KJOG.2011.54.5.247

A case of vaginally terminated fetus who had intracranial immature teratoma after transabdominal fetal cephalocentesis

Ji Young Kim, MD1, Yeo Jin Kwak, MD1, Sun-Ju Byun, MD, MS2, Chan-Wook Park, MD, PhD1, Joong Shin Park, MD, PhD1, Sung-Hye Park, MD, PhD2, Jong Kwan Jun, MD, PhD1, Hee Chul Syn, MD, PhD1

1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Corresponding author: Joong Shin Park, MD, PhD. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea. Tel: +82-2-2072-3199, Fax: +82-2-762-3599, jsparkmd@snu.ac.kr

Received 11 February 2011       Revised 1 April 2011       Accepted 5 April 2011

Copyright © 2011. Korean Society of Obstetrics and Gynecology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Congenital intracranial teratoma is a very rare kind of tumor. A fetus was diagnosed with a congenital intracranial teratoma and hydrocephalus at 20 weeks' gestation. On prenatal ultrasonography, the fetus showed a severe macrocephalic hydrocephalus, along with a huge, heterogenous intracranial mass in the posterior fossa. After fetal cephalocentesis was performed at 21 weeks' gestation, the pregnancy was terminated vaginally without any complication. On the postmortem examination, the pathologic report revealed an intracranial immature teratoma. We report a case with a brief review of the literature.

Keywords: Brain tumor, Congenital teratoma, Cephalocentesis, Hydrocephalus

Figures and Tables

Fig. 1
Prenatal ultrasonographic findings of the cranial transverse plane. Showing about 7.1 cm sized echogenic intracranial mass with ablation of normal brain structure.
kjog-54-247-g001
Fig. 2
Fetal enlarged cranium.
kjog-54-247-g002
Fig. 3
Specimen of fetal intracranial teratoma. There was 8×6×4 cm sized mass on posterior brain parenchyme. The mass had cystic and solid portion and contain some calcification.
kjog-54-247-g003
Fig. 4
Microscopic findings of intracranial teratoma. This teratoma is composed of variable immature and mature embryonal tissues. Immature neuroectodermal tissue (A), ciliated pseudostratified epithelium (B), immature cartilage (C), and liver parenchyme (D). (A, C, D: H&E, ×200) (B: H&E, ×400).
kjog-54-247-g004

References

1. Buetow PC, Smirniotopoulos JG, Done S. Congenital brain tumors: a review of 45 cases. AJR Am J Roentgenol. 1990. 155:587–593.
2. Isaacs H. Fetal brain tumors: a review of 154 cases. Am J Perinatol. 2009. 26:453–466.
3. Inwald D, Kempley S, Hird M. Congenital primitive neuroectodermal tumour presenting as obstructed labour. Arch Dis Child Fetal Neonatal Ed. 1998. 78:F222–F224.
4. Köksal Y, Varan A, Akalan N, Bostanci A, Cila A, Söylemezoglu F, et al. Congenital cerebellar primitive neuroectodermal tumor in a newborn. Am J Perinatol. 2006. 23:173–176.
5. Kim YS, Lee KY, Kang CS, Shim SI, Kim SM. Congenital intracranial teratoma with extension into oral cavity: an autopsy case. Korean J Pathol. 1990. 24:326–330.
6. Schlembach D, Bornemann A, Rupprecht T, Beinder E. Fetal intracranial tumors detected by ultrasound: a report of two cases and review of the literature. Ultrasound Obstet Gynecol. 1999. 14:407–418.
7. Pinto V, Meo F, Loiudice L, D'Addario V. Prenatal sonographic imaging of an immature intracranial teratoma. Fetal Diagn Ther. 1999. 14:220–222.
8. Woodward PJ, Sohaey R, Kennedy A, Koeller KK. From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 2005. 25:215–242.
9. Schwartz S, Raffel LJ, Sun CC, Waters E. An unusual mosaic karyotype detected through prenatal diagnosis with duplication of 1q and 19p and associated teratoma development. Teratology. 1992. 46:399–404.
TOOLS
Similar articles