Abstract
Primary pulmonary hypertension is a rare disorder and rarely present in pregnant woman, but it make high risk of maternal morbidity and mortality. When a woman with subclinical primary pulmonary hypertension is pregnant, physiologic increase in maternal plasma volume aggravates pulmonary pressure cause cardiac arrest and maternal death. We diagnosed primary pulmonary hypertension in parous woman who didn't present at any symptom during pregnancy but had dyspnea 7 days after preterm vaginal delivery at 30 weeks 6 days. We report this case with brief review of literatures.
References
1. Pauwaa S, Machado RF, Desai AA. Survival in pulmonary arterial hypertension: a brief review of registry data. Pulm Circ. 2011. 1:430–431.
2. Robinson JN, Banerjee R, Landzberg MJ, Thiet MP. Inhaled nitric oxide therapy in pregnancy complicated by pulmonary hypertension. Am J Obstet Gynecol. 1999. 180:1045–1046.
3. Lam GK, Stafford RE, Thorp J, Moise KJ Jr, Cairns BA. Inhaled nitric oxide for primary pulmonary hypertension in pregnancy. Obstet Gynecol. 2001. 98:895–898.
4. Rubin LJ. Primary pulmonary hypertension. Chest. 1993. 104:236–250.
5. Weiss BM, Maggiorini M, Jenni R, Lauper U, Popov V, Bombeli T, et al. Pregnant patient with primary pulmonary hypertension: inhaled pulmonary vasodilators and epidural anesthesia for cesarean delivery. Anesthesiology. 2000. 92:1191–1194.
6. Walmrath D, Schermuly R, Pilch J, Grimminger F, Seeger W. Effects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension. Eur Respir J. 1997. 10:1084–1092.
7. Johnson SR, Granton JT. Pulmonary hypertension in systemic sclerosis and systemic lupus erythematosus. Eur Respir Rev. 2011. 20:277–286.
8. Chung WJ. Treatment of pulmonary hypertension. Korean J Med. 2010. 78:28–35.
9. Seo HS, Lee NH. Diagnosis and assessment of pulmonary arterial hypertension. Korean J Med. 2010. 78:5–13.
10. Kim H. Diagnosis and treatment of idiopathic pulmonary arterial hypertension. Korean J Med. 2006. 71:4–9.
11. Kim MJ. Overview and evaluation of pulmonary hypertension. J Korean Pediatr Cardiol Soc. 2006. 10:225–234.
12. Hill LL, De Wet CJ, Jacobsohn E, Leighton BL, Tymkew H. Peripartum substitution of inhaled for intravenous prostacyclin in a patient with primary pulmonary hypertension. Anesthesiology. 2004. 100:1603–1605.
13. Monnery L, Nanson J, Charlton G. Primary pulmonary hypertension in pregnancy: a role for novel vasodilators. Br J Anaesth. 2001. 87:295–298.
14. Kramer MR. Combination treatment in pulmonary arterial hypertension. Harefuah. 2011. 150:383–388.