Journal List > Korean J Gastroenterol > v.65(3) > 1007352

Lee and Jun: Nonselective β Blockers in Decompensated Cirrhosis: When to Start and for How Long?

Abstract

Article

Nonselective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

References

1. Sersté T, Melot C, Francoz C, et al. Deleterious effects of be-ta-blockers on survival in patients with cirrhosis and refractory ascites. Hepatology. 2010; 52:1017–1022.
crossref
2. Mandorfer M, Bota S, Schwabl P, et al. Nonselective β blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis. Gastroenterology. 2014; 146:1680–1690.e1.
crossref
3. Hernández-Gea V, Aracil C, Colomo A, et al. Development of ascites in compensated cirrhosis with severe portal hypertension treated with β-blockers. Am J Gastroenterol. 2012; 107:418–427.
crossref
4. Senzolo M, Cholongitas E, Burra P, et al. Beta-blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis. Liver Int. 2009; 29:1189–1193.
5. Krag A, Wiest R, Albillos A, Gluud LL. The window hypothesis: haemodynamic and non-haemodynamic effects of β-blockers improve survival of patients with cirrhosis during a window in the disease. Gut. 2012; 61:967–969.
6. Ruiz-del-Arbol L, Urman J, Fernández J, et al. Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis. Hepatology. 2003; 38:1210–1218.
crossref
7. Arvaniti V, D'Amico G, Fede G, et al. Infections in patients with cirrhosis increase mortality four-fold and should be used in de-termining prognosis. Gastroenterology. 2010; 139:1246–1256. e5.
crossref
8. Sersté T, Francoz C, Durand F, et al. Beta-blockers cause para-centesis-induced circulatory dysfunction in patients with cirrhosis and refractory ascites: a cross-over study. J Hepatol. 2011; 55:794–799.
crossref
9. Galbois A, Das V, Thabut D, et al. Beta-blockers have no effect on outcomes in patients with cirrhosis and severe infections. Hepatology. 2011; 53:1412–1413.
crossref
10. Bendtsen F, Henriksen JH, S⊘rensen TI. Propranolol and haemodynamic response in cirrhosis. J Hepatol. 1991; 13:144–148.
crossref
11. Groszmann RJ, Garcia-Tsao G, Bosch J, et al. Portal Hypertension Collaborative Group. Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med. 2005; 353:2254–2261.
crossref
12. Krag A, Bendtsen F, Henriksen JH, M⊘ller S. Low cardiac output predicts development of hepatorenal syndrome and survival in patients with cirrhosis and ascites. Gut. 2010; 59:105–110.
crossref
TOOLS
Similar articles