Multiple Neuroendocrine Tumor of the Distal Ileum

Seung Min Lee; Jong Hoon Lee

doi:10.4166/kjg.2013.61.2.110

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Lee and Lee: Multiple Neuroendocrine Tumor of the Distal Ileum

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Korean J Gastroenterol 2013;61(2):110-113.

Published online: 4 October 2013

DOI: https://doi.org/10.4166/kjg.2013.61.2.110

Multiple Neuroendocrine Tumor of the Distal Ileum

Seung Min Lee, Jong Hoon Lee

Department of Internal Medicine, Dong-A University School of Medicine, Busan, Korea

Correspondence to: Jong Hoon Lee, Department of Internal Medicine, Dong-A University School of Medicine, 32 Dongdaeshin-dong 3-ga, Seo-gu, Busan 602-714, Korea. Tel: +82-51-240-2893, Fax: +82-51-242-5852, E-mail: jh2002@dau.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1.

Abdominal CT showing homogeneously enhancing mass in the distal ileum with multiple lymph node enlargement, small bowel mesentery and mesenteric haziness (arrow).

Fig. 2.

Capsule endoscopic finding. Luminal protruding masses were observed at the ileum.

Fig. 3.

PET-CT showing hypermetabolic malignancy in the ileum with multiple regional lymph node metastasis in the small bowel mesentery (arrow).

Fig. 4.

The small intestinal wall showed five nodular masses, measuring up to 4 × 3 cm in dimension (A), and each of masses had grayish fish-fresh like cut curface (B). (C) On microscope, the tumor was composed of uniform neuroendocrine cells with scant, lightly eosionphilic cytoplasm, arranged in nests and trabeculae (H&E, ×200). The tumor cells invaded through the muscularis propria into the subserosal tissue (inset). (D) The tumor cells showed intense cytoplasmic immunoreactivity with chromogranin A (×200).

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