Clinical Features of Ischemic Colitis: Related to Age, Constipation, Irritable Bowel Syndrome

Nam-Chul Jin; Yeon-Ju Kim; Young-A Song; Kyung-Won Yoon; Sun-Young Park; Sung-Bum Cho; Wan-Sik Lee; Chang-Hwan Park; Hyun-Soo Kim; Sung-Kyu Choi; Jong-Sun Rew

doi:10.4068/cmj.2008.44.3.144

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Jin, Kim, Song, Yoon, Park, Cho, Lee, Park, Kim, Choi, and Rew: Clinical Features of Ischemic Colitis: Related to Age, Constipation, Irritable Bowel Syndrome

Original Article

Chonnam Medical Journal

Chonnam Medical Journal 2008; 44(3): 144-150.

Published online: 18 December 2008

DOI: https://doi.org/10.4068/cmj.2008.44.3.144

Clinical Features of Ischemic Colitis: Related to Age, Constipation, Irritable Bowel Syndrome

Nam-Chul Jin, Yeon-Ju Kim, Young-A Song, Kyung-Won Yoon, Sun-Young Park, Sung-Bum Cho, Wan-Sik Lee¹, Chang-Hwan Park¹, Hyun-Soo Kim¹, Sung-Kyu Choi¹, Jong-Sun Rew¹

Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.

¹Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea.

Corresponding author (dshskim@jnu.ac.kr)

Accepted 19 November 2008

Abstract

Ischemic colitis (IC) is a frequent disorder in older person but it is usually self-limiting disease responding to conservative treatment. Recently, incidence of IC increase in gradual at broad range of age, especially to young age, relatively. The aims of this study are to evaluate clinical characteristics of patients with IC treated in Chonnam National University Hospital (CNUH). Between January 2000 and May 2007 in CNUH, 67 patients (30 males, 37 females) with IC were enrolled. We compared clinical features between young and elderly, group with IC accompanied with constipation, irritable bowel syndrome (IBS), or not. Among the 67 IC patients, most patients (79.1%) are older than fifty years and suffer from abdominal pain (71.6%), hematochezia (59.7%) and diarrhea (38.8%). Most of all are diagnosed through colonoscopy (79.1%) or abdominal CT (65.6%) and recovered by conservative treatment (89.6%). Risk factors for IC are atherosclerotic vascular diseases (56.7%), vasoactive medicine (31.3%), IBS (11.9%) and constipation (13.4%). Older age with IC has more frequently associated with risk factors. At the comparison associated with IBS, 3 patients (37.5%) with IBS and 4 patients (6.8%) without IBS have surgery (p=0.008). At the comparison associated with constipation, 45 patients (77.6%) without constipation and 3 patients (33.3%) with constipation have abdominal pain. The results suggest that the presence of IBS or constipation may not be associated with frequency or severity of IC. But more large scaled epidemiologic study was needed.

Keywords: Colitis, Ischemic, Constipation, Irritable bowel syndrome

Figures and Tables

Table 1

Clinical features of ischemic colitis patients^*

^*Patients with ischemic colitis are 67;^†Constipation includes constipation type of irritable bowel syndrome and functional constipation.

Table 2

Irritable bowel syndrome^*and its subtype among Ischemic colitis

^*Patients with IBS among IC patients are 8.

Table 3

Clinical features of ischemic colitis patients: comparison between young and elderly groups

^*Constipation include constipation type of irritable bowel syndrome and functional constipation;^†Patients of young group are less than 60 year old (n=27);^‡Patients of elderly group are more than 60 year old (n=40).

Table 4

Clinical features of ischemic colitis patients: comparison between IBS (irritable bowel syndrome) and non-IBS groups

^*Patients with IBS among IC patients are 8;^†Patients without IBS among IC patients are 59.

Table 5

Clinical features of ischemic colitis patients: comparison between constipation^*and non-constipation groups

^*Constipation include constipation type of irritable bowel syndrome and functional constipation;^†Patients with constipation among IC patients are 9;^‡Patients without constipation among IC patients are 58.

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