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Kwon, Kim, Hur, Park, Lee, and Lee: Solitary Extramedullary Plasmacytoma of Thyroid in Hashimoto's Thyroiditis: Mimicking Benign Cystic Nodule on Ultrasonography
Head and Neck Radiology

Journal of the Korean Society of Radiology 2013; 69(5): 347-350.

Published online: 8 November 2013

DOI: https://doi.org/10.3348/jksr.2013.69.5.347

Solitary Extramedullary Plasmacytoma of Thyroid in Hashimoto's Thyroiditis: Mimicking Benign Cystic Nodule on Ultrasonography

Yohan Kwon, MD1, Soo Jin Kim, MD1, Joon Ho Hur, MD1, Sung Hee Park, MD1, Sun Jin Lee, MD1, Tae Jin Lee, MD2

1Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

2Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

Corresponding author: Soo Jin Kim, MD. Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul 156-755, Korea. Tel. 82-2-6299-3220, Fax. 82-2-6263-1557, ksj1567@hanmail.net

Received 2 July 2013       Accepted 7 August 2013

Copyright © 2013 The Korean Society of Radiology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Solitary extramedullary plasmacytoma (SEP) of the thyroid is uncommon and mostly occur in patients with a Hashimoto's thyroiditis (82%). We present a case on SEP of thyroid in Hashimoto's thyroiditis, which mimics growing benign cystic masses on serial ultrasonography.

Keywords: Solitary Extramedullary Plasmacytoma, Hashimoto's Thyroiditis, Thyroid Cyst, Thyroid, Ultrasound

Figures and Tables

Fig. 1
Thyroid ultrasonography image of one year ago. There is 0.5 cm sized benign looking cystic lesion (arrow) in right lobe of thyroid gland. The background thyroid tissue shows multinodular hyperplasia.
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Fig. 2
Thyroid ultrasonography and enhanced neck CT images.
A, B. Transverse and longitudinal scan image of thyroid gland. There is an increase in cystic lesion (arrows) measured with 1.3 cm and the echogenicity of internal tissue has increased.
C. Axial CT image shows relatively low enhanced mass (arrowheads) in right thyroid lobe.
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Fig. 3
Histopathologic findings of the nodule after total thyroidectomy.
A. The specimen shows demarcation of the tumor from the thyroid parenchyma (H&E, × 100).
B. This mass is composed of plasmacytoid cells. Histologic finding is consistent with plasmacytoma (H&E, × 400).
jksr-69-347-g003
Fig. 4
Immunohistochemical stainings for lambda (A), CD138 (B), and CD79a (C) show positive immunoreactivity, however negative immunoreactivity in CD20 (D).
jksr-69-347-g004

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