Atypical Image of Focal Nodular Hyperplasia: Central Defect on Hepatobiliary Phase of Liver Magnetic Resonance Imaging

Young Sup Shim; Seung Joon Choi

doi:10.4166/kjg.2015.65.3.190

Journal List > Korean J Gastroenterol > v.65(3) > 1007351

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Shim and Choi: Atypical Image of Focal Nodular Hyperplasia: Central Defect on Hepatobiliary Phase of Liver Magnetic Resonance Imaging

Image of the Month

Korean J Gastroenterol 2015;65(3):190-193.

Published online: 4 October 2015

DOI: https://doi.org/10.4166/kjg.2015.65.3.190

Atypical Image of Focal Nodular Hyperplasia: Central Defect on Hepatobiliary Phase of Liver Magnetic Resonance Imaging

Young Sup Shim, Seung Joon Choi

Department of Radiology, Gachon University Gil Medical Center, Incheon, Korea

Correspondence to: Young Sup Shim, Department of Radiology, Gachon University Gil Medical Center, 21 Namdong-daero 774beon-gil, Namdong-gu, Incheon 405-760, Korea. Tel: +82-32-460-3043, Fax: +82-32-460-3065, E-mail: 0903gdf@gmail.com

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

References

1. Wanless IR, Mawdsley C, Adams R. On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology. 1985; 5:1194–1200.

2. Nguyen BN, Fléjou JF, Terris B, Belghiti J, Degott C. Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol. 1999; 23:1441–1454.

3. Brancatelli G, Federle MP, Grazioli L, Blachar A, Peterson MS, Thaete L. Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. Radiology. 2001; 219:61–68.

4. Kamel IR, Liapi E, Fishman EK. Focal nodular hyperplasia: lesion evaluation using 16-MDCT and 3D CT angiography. Am J Roentgenol. 2006; 186:1587–1596.

5. Hussain SM, Terkivatan T, Zondervan PE, et al. Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis. Radiographics. 2004; 24:3–17. discussion 18–19.

6. Grazioli L, Bondioni MP, Haradome H, et al. Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis. Radiology. 2012; 262:520–529.

7. Suh CH, Kim KW, Kim GY, Shin YM, Kim PN, Park SH. The diagnostic value of Gd-EOB-DTPA-MRI for the diagnosis of focal nodular hyperplasia: a systematic review and meta-analysis. Eur Radiol. 2014. doi: 10.1007/s00330-014-3499-9.

8. Eisenberg LB, Warshauer DM, Woosley JT, Cance WG, Bunzendahl H, Semelka RC. CT and MRI of hepatic focal nodular hyperplasia with peripheral steatosis. J Comput Assist Tomogr. 1995; 19:498–500.

9. Fujiwara H, Sekine S, Onaya H, Shimada K, Mikata R, Arai Y. Ring-like enhancement of focal nodular hyperplasia with hep-atobiliary-phase Gd-EOB-DTPA-enhanced magnetic resonance imaging: radiological-pathological correlation. Jpn J Radiol. 2011; 29:739–743.

10. Yoon JH, Kim JY. Atypical findings of focal nodular hyperplasia with gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging. Iran J Radiol. 2014; 11:e9269.

11. Yoneda N, Matsui O, Kitao A, et al. Hepatocyte transporter ex-pression in FNH and FNH-like nodule: correlation with signal intensity on gadoxetic acid enhanced magnetic resonance images. Jpn J Radiol. 2012; 30:499–508.

Fig. 1.

CT images of focal nodular hyperplasia. A lesion shows strong enhancement (arrow) on arterial phase (A) and has isoattenuation (arrow) on delayed phase of dynamic contrast-enhance CT (B).

Fig. 2.

MRI images of focal nodular hyperplasia (arrows). (A) Central scar in the lesion has bright high signal intensity on T2-weighted image of MRI. Arterial enhancement of lesion on MRI (B) is similar to that of CT scan, but on delayed image on MRI, there is peripheral enhancement and central low signal intensity (C). (D) The central portion of the lesion is noted by defect on hepatobiliary phase.

TOOLS

Similar articles