Journal List > Ewha Med J > v.12(1) > 1082905

TOOLS
Sung: The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue
Original Article

The Ewha Medical Journal 1989; 12(1): 7-11.

Published online: 24 July 2015

DOI: https://doi.org/10.12771/emj.1989.12.1.7

The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue

Nak Eung Sung

Department of Biochemistry, College of Medicine, Ewha Womans University, Korea.

Corresponding author: Nak Eung Sung. Department Biochemistry, College of Medicine, Ewha Womans University, Korea.

Copyright © 1989. Ewha Womans University School of Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

To evaluate the effect of BHA and BHT on liver tissue, BHA and BHT, 100mg and 200mg/kg B.W. respectively, were given to experimental animals for 4 months.
Microsomal cytochrome P-450, cytochrome b5, cytochrome C reductase activity and lipid peroxidation of liver tissue of experimental animal were measured.
The results were as follow ;
1) Cytochrome P-450 increased significantly in experimental group given BHA but cytochrome b5 did not.
2) Cytochrome oxidnse activity increased moderately in BHA group but decreased in BHT group. From these finding, it can be assumed, that BHA and BHT has no great effect on human tissue.

TOOLS
Similar articles