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Sung and Rho: The Effects of Hemodynamic Findings on Development of Pulmonary Vascular Changes in Patients with Ventricular Septal Defect
Original Article
Korean Circulation Journal

Korean Circulation Journal 1989; 19(4): 740-748.

Published online: 31 December 1989

DOI: https://doi.org/10.4070/kcj.1989.19.4.740

The Effects of Hemodynamic Findings on Development of Pulmonary Vascular Changes in Patients with Ventricular Septal Defect

Sang Hyun Sung, M.D., Joon Ryang Rho, M.D.

Copyright © 1989 The Korean Society of Circulation

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Evlauation of pulmonary vascular changes and pre-and postoperative hemodynamic findings were performed in 25 patients who had ventricular septal defect associated with sevese pulmonary hypertension.
Lung biopsy were done preoperatively in two patients and during operation in twenty three patients. Also the postoperative systemic and polmonary arterial pressure were obtained about 10-20 minutes after the cardiopulmonary bypass.
The results were as follow:
1) There was no relationship between the severity of pulmonary vascular changes(Health-Edwards classification) and the patients age(X2=4.4427, P=0.2175).
2) There was a good correlation between preoperative ratio of pulmonary to systemic vascular resistance(Rp/Rs) and ratio of pre-and postoperative pulmonary to systemic arterial pressure(r=0.4846, P<0.05).
3) There was a significant correlation between the degree of medial wall thickness and preoperative Rp/Rs(r=0.6535, P<0.005).
4) There was no correlation between perioperative hemodynamic findings and medial wall thickness in the patients aged below 2 years.

Keywords: Ventricular septal defect, Pulmonary hypertension, Lung biopsy

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