Journal List > Korean J Urol > v.47(5) > 1069905

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Jo, Jo, Lee, Lee, Kim, Lee, and Kim: A Young Man with Primary Small Cell Carcinoma of the Urinary Bladder
Case Report
Korean Journal of Urology

Korean Journal of Urology 2006; 47(5): 556-558.

Published online: 31 May 2006

DOI: https://doi.org/10.4111/kju.2006.47.5.556

A Young Man with Primary Small Cell Carcinoma of the Urinary Bladder

Sung-Whan Jo, In-Chang Jo, Ok-Jun Lee1, Sang-Cheol Lee, Yong-Tae Kim, Hyung Lae Lee, Wun-Jae Kim

Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea.

1Department of Pathology, Chungbuk National University College of Medicine, Cheongju, Korea.

Corresponding author (wjkim@chungbuk.ac.kr)

Received 9 November 2005       Accepted 1 February 2006

Copyright © 2006 The Korean Urological Association

Abstract

Small cell carcinoma of the urinary bladder is a rare finding. It is characterized by an aggressive clinical course with early metastasis and it tends to affect the elderly who have significant comorbidities. The mean age of these patients is 67.8 years. The prognosis of small cell carcinoma of the urinary bladder is poor because its behavior is more aggressive than bladder transitional cell carcinoma. On the pathologic finding, small cell carcinoma of the urinary bladder is usually combined with transitional cell carcinoma or adenocarcinoma in approximately 40% of cases. We reported here on a case of the primary pure small cell carcinoma of the urinary bladder in a 26 year-old man who was managed with partial cystectomy and combined chemotherapy using cisplatin.

Keywords: Small cell carcinoma, Bladder

Figures and Tables

Fig. 1
Computed tomography scan shows a 4×4cm sized intravesical polypoid mass with internal calcification in the urinary bladder. *shows a heterogenous enhancing mass protruding from the anterior bladder wall into the intravesical cavity.
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Fig. 2
Gross finding of the tumor specimen shows a well-marginated mass.
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Fig. 3
(A) The tumor consists of small, rather uniform cells with nuclear molding, scant cytoplasm and inconspicuous nucleoli. Frequent mitoses are observed (HE, ×400). (B) The tumor cells show positive immunoreactivity for synaptophysin (Immunohistochemistry, ×400).
kju-47-556-g003

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