Journal List > Infect Chemother > v.42(1) > 1035059

Park and Han: General Features and Post-Exposure Prophylaxis of Rabies

Abstract

Rabies is a representative zoonotic disease caused by rabies virus. The discriminative features of rabies are broad range of hosts including humans, a wide variety of incubation periods ranging from a few weeks to more than a year, ability to bring about acute fetal consequence, and scare pathological lesions. Although rabies is fatal, it is preventable disease by vaccination and post-exposure prophylaxis (PEP). This review will focus on general features of rabies, and immunoglobulin and vaccines for PEP.

Figures and Tables

Figure 1
High- and suspect-risk regions of rabies. High-risk and suspect-risk regions are indicated in blue and light blue, respectively. The areas where rabies in humans and animals was reported since 1993 were designated as high-risk region of rabies.
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Figure 2
Guideline on post-exposure prophylaxis for animal bite patients (Korea CDC, 2007).
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Figure 3
Management of animals to determine post-exposure treatment in 2008. (A) Bite cases by animals vaccinated to rabies. (B) Bite cases by unvaccinated animals.
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Table 1
Laboratory confirmation of rabies (29)
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N, Number of sample

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