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Choi, Kang, Shin, Jee, Kim, Kim, and Shim: Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients
Original Article
Journal of Korean Medical Science

Journal of Korean Medical Science 1994; 9(2): 162-168.

Published online: 19 June 2009

DOI: https://doi.org/10.3346/jkms.1994.9.2.162

Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients

Yeong Jin Choi, Chang Suk Kang, Wan Shik Shin, Mi Kyoung Jee, Byoung Kee Kim, Sun Moo Kim, Sang In Shim

Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.

Copyright © 1994 The Korean Academy of Medical Sciences

Abstract

We report two cases of posttransplant malignant lymphoma(PTML) of B cell origin associated with Epstein-Barr virus(EBV) infection. They were a 52-year-old male and a 37 year-old-female, in whom intermediate-grade diffuse malignant lymphomas of large cell type developed in the submandibular area and jejunum, respectively. DNA and RNA in situ hybridization revealed the presence of EBV-specific DNA and RNA sequences in the tumor cells.

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