Abstract
Pernicious anemia is an autoimmune disease characterized by a gastric mucosal
defect which results in an insufficiency of intrinsic factor to facilitate the
absorption of the physiologic amount of cobalamin. Increased risk of cancers of
the stomach has been reported for patients with pernicious anemia. We report
here a case of a 65 year old woman who had been diagnosed as having pernicious
anemia 16 months previously, was receiving monthly vitamin B12 injections, and
developed early gastric cancer type IIa by routine follow-up gastroscopic
examination. This patient underwent endoscopic mucosal resection for an early
gastric cancer lesion with a free resection margin.