Journal List > J Korean Ophthalmol Soc > v.49(4) > 1008247

Sung, Lee, Kim, Choung, and Khwarg: A Case of Orbital Angioleiomyoma

Abstract

Purpose

To report a rare case of an angioleiomyoma involving the orbit.

Case summary

A 32-year-old male visited our clinic with pain and decreased visual acuity in the left eye, which had developed 1 month prior to admission. Best corrected visual acuity of the left eye had decreased to 0.7, and 3 mm of proptosis was observed. A 1×1 cm sized soft orbital mass was palpated on the lateral area of the left lower eyelid. Funduscopic examination of the left eye revealed multiple horizontal choroidal folds. On magnetic resonance imaging, a well-demarcated tumor was identified that showed hypointense signal intensity on a T1-weighted scan and hyperintense signal intensity on a T2-weighted scan. We performed anterior orbitotomy with an inferior conjunctival forniceal incision. The tumor was well encapsulated and easily dissected and could be completely removed. Histopathologic examination showed many vascular elements and intervascular fibrous stromas composed of spindle cells. The tumor was classified as angioleiomyoma.

Conclusions

Angioleiomyoma should be considered in the differential diagnosis of a well-circumscribed mass lesion involving the orbit.

References

1. Ramesh P, Annapureddy SR, Khan F, Sutaria PD. Angioleiomyoma: a clinical, pathological and radiological review. Int J Clin Pract. 2004; 58:587–91.
crossref
2. Matsuyama A, Hisaoka M, Hashimoto H. Angioleiomyoma: a clinicopathologic and immunohistochemical reappraisal with special reference to the correlation with myopericytoma. Hum Pathol. 2007; 38:645–51.
crossref
3. Hachisuga T, Hashimoto H, Enjoji M. Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer. 1984; 54:126–30.
crossref
4. Arat YO, Font RL, Chaudhry IA, Boniuk M. Leiomyoma of the orbit and periocular region: a clinicopathologic study of four cases. Ophthal Plast Reconstr Surg. 2005; 21:16–22.
5. Henderson JW, Harrison EG Jr. Vascular leiomyoma of the orbit: report of a case. Trans Am Acad Ophthalmol Otolaryngol. 1970; 74:970–4.
6. Stout AP. Solitary cutaneous and subcutaneous leiomyoma. Am J Cancer. 1937; 29:435–69.
crossref
7. Morimoto N. Angiomyoma: A clinicopathologic study. Med J Kagoshima Univ. 1973; 24:663–83.
8. Figueiredo EG, Gomes M, Vellutini E, et al. Angioleiomyoma of the cavernous sinus: case report. Neurosurgery. 2005; 56:411.
crossref
9. Wang CP, Chang WL, Sheen TS. Vascular leiomyoma of the head and neck. Laryngoscope. 2004; 114:661–5.
crossref
10. Gunduz K, Gunalp I, Erden E, Erekul S. Orbital leiomyoma: report of a case and review of the literature. Surv Ophthalmol. 2004; 49:237–42.
11. Goldberg RA, Shorr N, Arnold AC, Garcia GH. Deep transorbital approach to the apex and cavernous sinus. Ophthal Plast Reconstr Surg. 1998; 14:336–41.
crossref
12. Nall AV, Stringer SP, Baughman RA. Vascular leiomyoma of the superior turbinate: first reported case. Head Neck. 1997; 19:63–7.
crossref

Figure 1.
Preoperative MRI demonstrates a well‐ circumscribed oval mass occupying the inferolateral part of the left orbit. The tumor is hypointense on T1-weighted images (A, C) and hyperintense on T2-weighted images (B). The tumor shows gradual bright enhancement (D-F).
jkos-49-673f1.tif
Figure 2.
Light micrograph of excisional biopsy specimen. (A) Photomicrographs show many vascular channels and spindle-shaped cells (hematoxylin‐ eosin, ×10). (B) The dilated vascular channels have thin walls that are difficult to distinguish from intervascular stroma, and it is diagnosed as cavernous type (hematoxylin‐ eosin, ×100). (C) The nuclei of tumor cells have blunted‐ ends, and show no mitotic figures (hematoxylin‐ eosin, ×200). (D) The tumor cells show intense positive staining with SMA (SMA, ×100).
jkos-49-673f2.tif
TOOLS
Similar articles