Fibrin Glue for Conjunctival Closure in Pars Plana Vitrectomy

Eun Kyoung Lee; Jung Yeul Kim

doi:10.3341/jkos.2008.49.8.1283

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Lee and Kim: Fibrin Glue for Conjunctival Closure in Pars Plana Vitrectomy

Original Article

J Korean Ophthalmol Soc 2008;49(8):1283-1288.

Published online: 7 September 2008

DOI: https://doi.org/10.3341/jkos.2008.49.8.1283

Fibrin Glue for Conjunctival Closure in Pars Plana Vitrectomy

Eun Kyoung Lee, M.D.¹, Jung Yeul Kim, M.D.^1,²

Department of Ophthalmology, College of Medicine, Chungnam National University, Daejeon, Korea

Chungnam National University Research Institute for Medical Sciences, Daejeon, Korea

Address reprint requests to Jung Yeul Kim, M.D. Department of Ophthalmology, Chungnam National Hospital #640 Daesa-dong, Jung-gu, Daejeon 301-721, Korea Tel: 82-42-280-8433, Fax: 82-42-255-3745, E-mail: kimjy@cnu.ac.kr

Received 15 April 2008 Accepted 21 January 2008

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To investigate the efficacy of fibrin glue for conjunctival closure in vitrectomy.

Methods

Two hundred five eyes of 200 patients who underwent conjunctival closure for vitrectomy with a minimum follow-up period of six months were evlauated. Postopertive pain, foreign body sensation, tearing, subconjunctival hemorrhage, surgery time and complication were evaluated prospectively in 105 eyes of 100 patients undergoing surgery with fibrin glue, and in 100 eyes of 100 patients undergoing surgery with sutures.

Results

One day postoperatively, pain scores (p<0.05), foreign body sensation (p<0.05), tearing (p<0.05), and subconjunctival hemorrhage (p<0.05) were significantly lower in the fibrin glue group than in the suture group. One week postoperatively, the scores of foreign body sensation (p<0.05), tearing (p<0.05), subconjunctival hemorrhage (p<0.05) were significantly lower in the fibrin glue group than in the suture group. The mean surgery time in the fibrin glue group (2.2±0.5 minutes) was significantly shorter than that in the sutures group (7.4±0.6 minutes) (p<0.05).

Conclusions

The Use of fibrin glue for conjunctival closure in vitrectomy can reduce postoperative discomfort and surgical time. It is especially useful for a second operation or for cases with a thin, atrophic conjunctiva.

Keywords: Conjunctival closure, Fibrin glue, Vitrectomy

References

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Figure 1.

Clinical appearance of 2 eyes postoperative 3 day: conjunctival closure with Greenplast^® (A, B) and with 8-0 Vicryl (C, D).

Figure 2.

Day 1 postoperative signs and symptoms (average score) in the patients treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 3.

Week 1 postoperative signs and symptoms (average score) in the patients treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 4.

Day 1 postoperative signs and symptoms (average score) in the patients over 70 years old those had atrophic, thin conjunctiva treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 5.

Week 1 postoperative signs and symptoms (average score) in the patients over 70 years old those had atrophic, thin conjunctiva treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 6.

Day 1 postoperative signs and symptoms (average score) in the patients those had second operation treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 7.

Week 1 postoperative signs and symptoms (average score) in the patients those had second operation treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

Figure 8.

Operative time in the patients treated with glue compared with those treated with suture (* p<0.05, Mann- Whitney U test).

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