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Abstract
Purpose
We report here on the safety and efficacy of nephron-sparing radiofrequency ablation (RFA) for treating renal tumor.
Materials and Methods
Starting June 2004, a total of 14 patients underwent RFA for renal tumor during the following 3 years. Of these, 12 cases were followed up for at least 6 months postoperatively. Eight cases of combined computed tomography (CT) and ultrasonogram-guided percutaneous RFA, and four cases of intraoperative ultrasonography-guided laparo-scopic RFA were performed with mean follow-up of 18.2 months (range: 4-27 months). The treatment indications were a localized, small (＜4cm), solid renal mass in the elderly patients and those patients with co-morbid conditions. Physical examination, CBC, determining the serum creatinine levels and urine analysis were performed for the follow-up laboratory study and kidney CT was performed at day 1, 1 week, 1 month, 3 months, 6 months and 1 year after ablation and thereafter semi-annually. The mean follow-up duration was 18.2 months (range: 4-27 months).
Results
All the patients underwent successful RFA without any serious events. Four patients had mild perinephric hematoma on the follow-up CT scan and there was one case of mild gross hematuria postoperatively. With a mean follow-up of 18.2 months, two patients showed residual tumor at 3 months & 22 months, respectively, on the follow-up contrast-enhanced CT after the first tumor ablation. One patient underwent a second RFA and another patient underwent laparoscopic radical nephrectomy, and no residual tumor was seen on the follow-up CT. Distant metastasis was not found in any cases and all the patients are alive on serial follow-up.
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Fig. 1.
(A) The follow up CT scan image 24 hours after radiofrequency ablation (RFA) shows slightly enhanced peripheral lesion. (B) The follow up CT image 1 month after RFA shows no contrast enhancement of the left renal tumor, but a slightly increased size. (C) The follow up CT image 6 month after RFA shows a decreased tumor size compared to that immediately after RFA. (D) The follow up CT image 9 month after RFA shows a more decreased tumor size.
Table 1.
The patient characteristics and pre-operative status of the 12 cases
Table 2.
Results of radiofrequency ablation in the 12 patients
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