Park DU, et al.

This review describes the Household Humidifier Disinfectant Tragedy (HHDT) in Korea, which highlights the need for improved national poison prevention and surveillance. This study aims to identify necessary changes in chemical poisoning prevention regulations by comparing international poison control center (PCC) trends and outlining critical elements for an advanced Korean PCC system. The authors revealed deficiencies in Korea's legislation, toxicological data management, and surveillance. Recommendations include a centralized toxic substances database, mandatory or voluntary poisoning case reporting, real-time alerts, health organization collaboration, and follow-up of poisoning cases. Establishing a comprehensive PCC with toxicovigilance in Korea could serve as a model for other countries.

Chun BC, et al.

Guidelines recommend vaccination for those recovered from SARS-CoV-2 to prevent reinfection, but comprehensive evaluation studies are limited. This study aimed to assess vaccine effectiveness against SARS-CoV-2 reinfection based on primary and booster vaccination status and methods. Conducted in Seoul from January 2020 to February 2022, it included 7,678 re-infected cases and controls. Analysis showed that booster doses significantly reduced reinfection rates compared to basic vaccination. The mRNA, Nova, and heterologous vaccinations were more effective than no vaccination, while vector vaccinations had higher reinfection rates compared to mRNA. Completing the basic vaccination series provided significant protection, enhanced by booster doses.

Choe YJ, et al.

This study reviewed the status of the Korea Expert Committee on Immunization Practices (KECIP) and gathered expert opinions through surveys and consultations. Among 19 respondents, most favored keeping the current member count and supported subcommittees. Opinions varied on term length, vaccine manufacturers’ representation, and the chairperson’s role, but there was consensus on the need for expertise, transparency, and fair proceedings. The study highlights KECIP’s crucial role in guiding immunization policies, emphasizing the need to enhance its capacity to address public health challenges and maintain successful programs in South Korea.

Kim YJ, et al.

This study analyzed the effects of an antimicrobial stewardship program (ASP) on antimicrobial-resistant pathogens in bacteremia, antimicrobial use, and mortality in pediatric patients. A retrospective single-center study included pediatric inpatients under 19 years old from 2001 to 2019. ASP began in June 2008, dividing the study into pre-intervention (2001–2008) and post-intervention (2009–2019) periods. Results showed an increase in ESBL-producing E. coli and K. pneumoniae from 17% to 35% post-intervention (P < 0.001). However, antimicrobial use significantly decreased (delta slope = −16.5, P = 0.049), and the 30-day mortality rate remained stable at 10% (P = 0.881). ASP reduced antimicrobial use without increasing mortality.