The purpose of this study was to explore the relationships among women's total symptom distress, uncertainty and quality of life in women with endometriosis.

A total of 121 women who had been diagnosed with endometriosis was given a questionnaire. Data was collected from August 2004 to January 2005. The data was analyzed by frequency, mean, t-test, ANOVA, Pearson correlation coefficient, and multiple linear regression analysis using SPSS WIN 10.0 software.

The mean score of TSD was 3.23. 'Menstrual cramping' showed the highest score. The mean score of uncertainty, and quality of life of the subject was 56.6, and 38.3 respectively. TSD was significantly related with coffee intake and uncertainty was significantly related with marital status, economic status, alcohol intake, diagnosis after period, and family history. Quality of life was significantly related with age, and dysmenorrhea. There were significant relationships between total symptom distress and uncertainty, and quality of life. There were significant relationship between uncertainty and quality of life.

Endometriosis symptoms showed a significant relationship with uncertainty and quality of life. This study will help to manage women with endometriosis.