Journal List > Korean J Gynecol Oncol Colposc > v.4(1) > 1123767

Kang, Koh, Kim, Kim, Song, and Lee: Diagnosis and Management of Microinvasive Carcinoma of the Cervix : A 10-years experience in the Seoul National University Hospital

Abstract

Microinvasive squamous cellI carcinoma of the cervix is a subject assoicated with decades of confusion, multiplicity af definitions, and a variety of therapeutic approaches. The diversity of therapeutic approaches to microinvasive eervical carcinoma reflects uneasiness in reconciling two aspects of the disease : The morbidity associated with radieal therapeutic measures must be weighed against the probability of lymph node metastasis, recurrence, and death from cancer. So in this study, we adress these issuses by reviewing our 10 years experinece from Feb, 1982, to Feb. 1992. We evaluated 59 cases of patient histologically proven by microinvasive carcinomm of the cervix and treated by operation including total abdominal hystereetomy, modified radietl and radical hysterectomy with pelvic lymph node dissection. We use the definitio as stromal penetration by carcinoma not exceeding a depth of 3mm from the surface at the point of origin. The mean age of patients was 42.0 years old at the time of diagnosis. (Sun Bourm Kang, et al.: Diagnosis and Management of Micromvasive Carcinoma of the Cervix; A 1Q-years Experience in the ouJ National Unlversity Hospital) The sensitivity of diagnosis by pap smew was 84.7% but there was no relationship between pap srnear and depth of invasion. The sensitivity of punch biogey was statistically higher in deeper invasion, Depth of invasion was 1mm or less in 1.5 patients, 1.1-2.0mm in 19 patients, and 2.1-3.0mm in 25 patiente. There was no lymph v glar space invesion. The inflammation was more severe and the pattern of invasion was more onfluent with deeper invesion. Pelvic lymph node dissection was done in 4H patients and there was no lymph node metastasis. Total abdominal hysterectomy was done in 15 cases of mieroinvasive cervix cancer patient, and 19 cases of patient were treated by total abdominal hysterectomy with pelvie lymph node dissection and 35 cases were treated by radical hystereetomy with pelvic lymph node di ction. And currently less radical theapeutic approaches has been used with the colpescopy. There was no reeurrenee in all cases and 5 year survival rate was 100%. so these data suggest that less radical therapy for these disease may be sufficient if the depth of invasion is less than 3mm.

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