Journal List > Korean J Pediatr Gastroenterol Nutr > v.2(2) > 1110598

Choe, Kim, and Seo: Seroepidemiology of H. pylori Infection in Normal Preschool Children

Abstract

PURPOSE

The aim of this study was to evaluate the prevalence of H. pylori infection in normal preschool children.

METHODS

Study population consisted of 220 preschool children aged 2 to 5 years in Seoul, Korea. We measured H. pylori specific IgG antibody using the GAP test IgG kit, and samples with concentrations greater than 20 U/ml were considered positive.

RESULTS

Of the 220 children, 5 (2.3%) were positive, and thirteen (5.9%) of 220 were equivocally probable positive.

CONCLUSION

The positive rate of H. pylori infection detected by specific IgG antibody in normal preschool children aged 2 to 5 years was approximately 2.3% to 8.2%. This prevalence rate is still high, compared to that of the West. A better knowledge of the transmission of H. pylori is crucial to formulate recommendations for lowering the rate.

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