Journal List > Korean J Pediatr Gastroenterol Nutr > v.11(2) > 1110130

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Park, Ko, Seo, Lee, Shin, Kang, and Kim: Nonalcoholic Fatty Liver Disease Progressing to Cirrhosis in an Obese Boy with Hypopituitarism
Case Report

Korean Journal of Pediatric Gastroenterology and Nutrition 2008; 11(2): 204-209.

Published online: 30 September 2008

DOI: https://doi.org/10.5223/kjpgn.2008.11.2.204

Nonalcoholic Fatty Liver Disease Progressing to Cirrhosis in an Obese Boy with Hypopituitarism

Ji Yong Park, Jae Sung Ko, Jeong Kee Seo, Ran Lee*, Choong Ho Shin, Gyeong Hoon Kang†, Woo Sun Kim‡

Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.

*Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.

†Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

‡Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.

jkseo@snu.ac.kr

Copyright © 2008 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition

Abstract

Non-alcoholic fatty liver disease (NAFLD) is typically associated with obesity and insulin resistance. Non-alcoholic steatohepatitis (NASH) is a more serious form of NAFLD. Although fibrosis is common in pediatric NASH, cirrhosis has been rarely reported. Patients with hypothalamic or pituitary dysfunction are at risk for obesity and insulin resistance with subsequent development of NAFLD. We report a case of NAFLD progressing to cirrhosis in an obese 16 year-old boy with hypopituitarism.

Keywords: Non-alcoholic fatty liver disease, Cirrhosis, Obesity, Hypopituitarism

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