The newborn human is the only mammalian who.se mother does not have a food supply ready for it's offspring at birth. From two to four days usually elapse before the mother's supply of milk appears, and during this period, some kind of artificial feeding should be supplied to the infants. Because of this factor, there has been continued debate for the past hundreds of years as to when the first feeding should be started. Accordingly, many experiments were car-ried out by scholars and because of these, pre-lacteal feedings were believed to be neces-sary. Many types of pre-lacteal feedings were tried and the conclusion was reached that glucose water was the best food for the first infants* feedings. Traditionally, This has been started 12 hours after birth. The causes for the 12 hours delay were thought to (1) provide rest for the infants; (2) prevent regurgitation and vomiting which tended to be prevalent during this time; (3) in cases of low weight infants, prevention of aspiration pneumonia. From recent studies of newborn physiology and as pediatric medicine has been rapidly ad-vancing, many studies have been carried out concerning the improvement of infant nutrition and the early feeding of infants has been emphasized. This author believes it would be very beneficial to try two different kinds of feedings for the infant, (1) experimental feedings and (2) comparative feeding, and during this period to investigate and compare the infants blood sugar level, hematocrit, gamma globulin level, weight changes and to observe the infant reaction in order to search for a more desirable feeding program. This study was conducted from January to March 1974 with data related to 40 healthy newborn infants (male 21, female 19: weight, 2. 79-4.20kg: gestation, 39~40 weeks) born at Ewha Womens University Hospital, and the results obtained were as follows: 1. At time of birth the blood sugar level from the cord sample averaged 88. 99mg/100mL, but the blood sugar level rapidly dropped after 2 to 3 hours and reached the fewest point after 10 to 11 hours (54.48mg/100ml) and rose again by the 24 hour time period (76. 80mg /100ml). Changes in the blood sugar level of the experimental groups and the compara-tive group was not significantly different until the 6 to 7 hour period, but by the 10 to 11 hour period the blood sugar levels of the experimental group (49.10mg/100ml) and the comparative group (49.70mg/100ml) were bwer than the remainder of the experimental groups. 2. There ware no significant weight changes between the tw.o groups. Average weight at birth was 3.35kg, but at the 24 hours period, birth weight averaged 3.29kg. (1.8% reduction of birth weight). It continually lowered until at 48 hours, average weight was 3.26kg (2. 7% reduction from birth weight.) 3. Hematocrit readings showed no significant difference between the groups. Hematocrit, the average value at birth, was 28. 07% and abruptly elevated to average 64. 35% at the 2 to 3 hour period, then slowly lowered to an average of 59.67% at the 6 to 7 hour period, 55.10% at the 10 to 11 hour period, and 53.70% at the 24 hour period. 4. At birth, average gamma globulin value averaged 1.39gm/100ml. and at the 24 hour period averaged 1.52gm/100mL revealing no significant difference between the two feeding groups. 5. Such factors as Voiding, passing of meconium, regurgitation and vomiting showed no significance between the two feeding groups. However, the number of infants voiding and passing meconium in the experimental groups during the first 12 hours was slightly greater. In general there was an increased tendency for regurgitation and. vomiting among a small group of the infants during the first 24 hours which thereafter decreased. 6. Fluid intake averaged 24. 38cc at the first feeding and increased to average 30.48cc at the third feeding and further increased to 73.00cc at the fifteenth feeding. Finally, it was suggested that the most reasonable method of early feeding is to give less than 25cc of 5% glucose water and/or 8% powdered milk at 8 to 9 hours after birth in order to prevent hypoglycemia and dehydration.