Relationship between the Level of Fibrinogen and the Signal Density on Brain Computed Tomography in the Chronic Subdural Hematoma

Won-Soo Son; Seong-Hyun Park; Dong-Hun Kang; Jaechan Park; Joo-Kyung Sung; Sung-Kyoo Hwang

doi:10.13004/jknts.2010.6.1.43

Journal List > J Korean Neurotraumatol Soc > v.6(1) > 1084078

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Son, Park, Kang, Park, Sung, and Hwang: Relationship between the Level of Fibrinogen and the Signal Density on Brain Computed Tomography in the Chronic Subdural Hematoma

Clinical Article

Journal of Korean Neurotraumatology Society 2010; 6(1): 43-47.

Published online: 30 June 2010

DOI: https://doi.org/10.13004/jknts.2010.6.1.43

Relationship between the Level of Fibrinogen and the Signal Density on Brain Computed Tomography in the Chronic Subdural Hematoma

Won-Soo Son, MD, Seong-Hyun Park, MD, Dong-Hun Kang, MD, Jaechan Park, MD, Joo-Kyung Sung, MD, Sung-Kyoo Hwang, MD

Department of Neurosurgery, College of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.

Address for correspondence: Seong-Hyun Park, MD. Department of Neurosurgery, College of Medicine, Kyungpook National University, Kyungpook National University Hospital, 200 Dongdeok-ro, Jung-gu, Daegu 700-721, Korea. Tel: +82-53-420-5649, Fax: +82-53-423-0504, nsdoctor@naver.com

Received 26 January 2010 Revised 11 March 2010 Accepted 8 June 2010

Abstract

Objective

The purpose of this study was to evaluate the relationship between fibrinogen levels and computed tomography (CT) findings in patients who had chronic subdural hematomas (CSDHs).

Methods

The study group was composed of 12 consecutive patients who had CSDH between January and December 2006. Patients with CSDH were divided on the basis of CT findings into group A (layering, mixed type) and group B (low, iso type). We performed surgery and obtained a sample from the subdural hematoma for measurement of the concentration of fibrinogen.

Results

The mean level of fibrinogen was 57.3 mg/dL in group A, and in <25 mg/dL group B. The concentration of fibrinogen was significantly higher in the layering and mixed type group than in the low and iso type group (p=0.003).

Conclusion

The layering, mixed type of CSDH demonstrated higher concentrations of fibrinogen in subdural hematomas than in low, iso type patients.

Keywords: Chronic subdural hematoma, Fibrinogen, Computed tomography

Figures and Tables

FIGURE 1

Computerized tomography scans demonstrate four types of chronic subdural hematoma: mixed density (A), layering (B), low density (C), iso density (D).

FIGURE 2

Graph showing the levels of fibrinogen in chronic subdural hematomas. The concentration of fibrinogen was significantly higher in the layering and mixed type group than in the low and iso type group (p=0.003).

TABLE 1

The mean levels of fibrinogen in chronic subdural hematoma and venous blood by computed tomographic findings

TABLE 2

The demographic data of fibrinogen level in chronic subdural hematoma

H-fibrinogen: hematoma fibrinogen level, S-fibrinogen: serum fibrinogen level

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