Journal List > J Nutr Health > v.47(1) > 1081342

J Nutr Health. 2014 Feb;47(1):23-32. Korean.
Published online February 28, 2014.  https://doi.org/10.4163/jnh.2014.47.1.23
© 2014 The Korean Nutrition Society
The effect of Sargassum confusum on reduction of body fat in obese women
Ki Sung Min,1 Daeseok Han,2 Sang-Oh Kwon,3 Kyung-Mok Yeo,3 Bok-Nam Kim,4 and Sun Yung Ly1
1Department of Food and Nutrition, Chungnam National University, Daejeon 305-764, Korea.
2Neo Food Resources Research Group, Korea Food Research Institute, Seongnam 463-746, Korea.
3R&D Center, S&D Co., Ltd., Chuncheon 200-160, Korea.
4Department of Tourism and Food Service Cuisine, Hallym Polytechnic University, Chuncheon 200-711, Korea.

To whom correspondence should be addressed. tel: +82-42-821-6838, Email: sunly@cnu.ac.kr
Received October 01, 2013; Revised December 01, 2013; Accepted January 23, 2014.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Purpose

This study was conducted in order to investigate the effect of Sargassum confusum extracts on the reduction of body fat for eight weeks in overweight women (BMI ≥ 23 kg/m2).

Methods

Subjects were classified by double-blind randomized trial as the control group (C group, n = 14) and the Sargassum confusum extract supplementation group (SC group, n = 16), which consumed 12 tablets per day. Questionnaires related to their health status were assessed twice (week 0 and week 8). Their dietary intake status was evaluated by 24-recall method and body compositions were measured using a bioelectrical impedance analyzer. In addition, we assessed the anti-obesity effect and the occurrence possibility of health risk factors during the supplementation periods by hematological and clinical analysis of blood.

Results

Waist circumference and body fat (%) were significantly decreased in the SC group. Serum leptin level was also significantly decreased in the SC group. Defecation frequency was significantly increased in the SC group. The above results indicate that Sargassum confusum extract supplementation improves overweight on visceral fat and blood leptin level by increasing bowel movement. These results imply a decrease of health risk factors in overweight women. Seven subjects withdrew from the study due to adverse events; however, no differences regarding adverse events were observed between the control and treatment group.

Conclusion

Therefore, Sargassum confusum extract is a plausible effective agent for body fat reduction in humans.

Keywords: Sargassum confusum; reduction of body fat ratio; overweight women

Tables


Table 1
Composition of the Sargassum confusum supplement
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Table 2
Baseline values and changes in anthropometric measurements and body composition by Sargassum confusum extract supplementation
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Table 3
Baseline values and changes in blood lipids and leptin levels and laboratory findings for safety of the subjects by Sargassum confusum extract supplementation
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Table 4
Baseline values and changes in daily nutrient intake levels by Sargassum confusum extract supplementation
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Table 5
Baseline values and changes in defecation frequency and water intakes by Sargassum confusum extract supplementation
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Table 6
Adverse effects during the intervention study
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Notes

This research was financially supported by the Ministry of Knowledge Economy (MKE) through the Research and Development for Regional Industry (10017622).

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